[HTML][HTML] Sculpting the dendritic landscape: Actin, microtubules, and the art of arborization

VR Ouzounidis, B Prevo, DK Cheerambathur - Current Opinion in Cell …, 2023 - Elsevier
Dendrites are intricately designed neuronal compartments that play a vital role in the
gathering and processing of sensory or synaptic inputs. Their diverse and elaborate …

Molecular mechanisms that mediate dendrite morphogenesis

JL Lefebvre - Current topics in developmental biology, 2021 - Elsevier
Neurons develop dendritic morphologies that bear cell type-specific features in dendritic
field size and geometry, branch placement and density, and the types and distributions of …

Homeostatic roles of the proteostasis network in dendrites

EN Lottes, DN Cox - Frontiers in Cellular Neuroscience, 2020 - frontiersin.org
Cellular protein homeostasis, or proteostasis, is indispensable to the survival and function of
all cells. Distinct from other cell types, neurons are long-lived, exhibiting architecturally …

PP2A phosphatase regulates cell-type specific cytoskeletal organization to drive dendrite diversity

S Bhattacharjee, EN Lottes, S Nanda… - Frontiers in molecular …, 2022 - frontiersin.org
Uncovering molecular mechanisms regulating dendritic diversification is essential to
understanding the formation and modulation of functional neural circuitry. Transcription …

Formin 3 directs dendritic architecture via microtubule regulation and is required for somatosensory nociceptive behavior

R Das, S Bhattacharjee, JM Letcher, JM Harris… - …, 2021 - journals.biologists.com
Dendrite shape impacts functional connectivity and is mediated by organization and
dynamics of cytoskeletal fibers. Identifying the molecular factors that regulate dendritic …

Basal autophagy is required for promoting dendritic terminal branching in Drosophila sensory neurons

SG Clark, LL Graybeal, S Bhattacharjee, C Thomas… - PloS one, 2018 - journals.plos.org
Dendrites function as the primary sites for synaptic input and integration with impairments in
dendritic arborization being associated with dysfunctional neuronal circuitry. Post-mitotic …

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Y Li, T Lu, P Dong, J Chen, Q Zhao, Y Wang… - Nature …, 2024 - nature.com
The Drosophila tracheal system is a favorable model for investigating the program of tubular
morphogenesis. This system is established in the embryo by post-mitotic cells, but also …

[HTML][HTML] Maintaining essential microtubule bundles in meter-long axons: a role for local tubulin biogenesis?

LM Pinho-Correia, A Prokop - Brain Research Bulletin, 2023 - Elsevier
Axons are the narrow, up-to-meter long cellular processes of neurons that form the
biological cables wiring our nervous system. Most axons must survive for an organism's …

Golgi-dependent copper homeostasis sustains synaptic development and mitochondrial content

C Hartwig, GM Méndez, S Bhattacharjee… - Journal of …, 2021 - Soc Neuroscience
Rare genetic diseases preponderantly affect the nervous system causing
neurodegeneration to neurodevelopmental disorders. This is the case for both Menkes and …

The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth

RA Alizzi, D Xu, CM Tenenbaum, W Wang… - PLoS genetics, 2020 - journals.plos.org
Dendritic arbor morphology influences how neurons receive and integrate extracellular
signals. We show that the ELAV/Hu family RNA-binding protein Found in neurons (Fne) is …