Identification of parameters representative of immune dysfunction in patients with severe and fatal COVID-19 infection: a systematic review and meta-analysis

R Qin, L He, Z Yang, N Jia, R Chen, J Xie, W Fu… - Clinical Reviews in …, 2023 - Springer
Abnormal immunological indicators associated with disease severity and mortality in
patients with COVID-19 have been reported in several observational studies. However …

Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases

T Kita, K Kitamura - Hypertension Research, 2022 - nature.com
Adrenomedullin (AM) is a vasodilative peptide with various physiological functions,
including the maintenance of vascular tone and endothelial barrier function. AM levels are …

[HTML][HTML] Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections

AH de Nooijer, P Pickkers, MG Netea, M Kox - Journal of Critical Care, 2023 - Elsevier
Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening
organ dysfunction caused by a dysregulated host response to infection'. It remains …

Biomarkers associated with cardiovascular disease in COVID-19

CC Kaufmann, A Ahmed, AL Burger, M Muthspiel… - Cells, 2022 - mdpi.com
Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan,
China and has since spread rapidly all over the world causing a global pandemic. While the …

Endothelium-associated biomarkers mid-regional proadrenomedullin and C-terminal proendothelin-1 have good ability to predict 28-day mortality in critically ill …

JAH van Oers, Y Kluiters, JAP Bons, M de Jongh… - Journal of critical …, 2021 - Elsevier
Purpose We assessed the ability of mid-regional proadrenomedullin (MR-proADM) and C-
terminal proendothelin-1 (CT-proET-1) to predict 28-day mortality in critically ill patients with …

[HTML][HTML] Circulating MR-proADM levels, as an indicator of endothelial dysfunction, for early risk stratification of mid-term mortality in COVID-19 patients

LG de Guadiana-Romualdo, MM Martínez… - International Journal of …, 2021 - Elsevier
Objectives Thromboinflammation, resulting from a complex interaction between
thrombocytopathy, coagulopathy, and endotheliopathy, contributes to increased mortality in …

Comparison of presepsin and Mid-regional pro-adrenomedullin in the diagnosis of sepsis or septic shock: a systematic review and meta-analysis

J Liang, Y Cai, Y Shao - BMC Infectious Diseases, 2023 - Springer
Background The early diagnosis of sepsis is hampered by the lack of reliable laboratory
measures. There is growing evidence that presepsin and Mid-regional pro-adrenomedullin …

The impact of body composition on mortality of COVID-19 hospitalized patients: A prospective study on abdominal fat, obesity paradox and sarcopenia

E Graziano, M Peghin, M De Martino, C De Carlo… - Clinical Nutrition …, 2022 - Elsevier
Background & aims Obesity has been described as a predisposing risk factor to severe
forms of COVID-19, but conflicting results are emerging on its real impact on the mortality of …

Identification of COVID-19 patients at risk of hospital admission and mortality: a European multicentre retrospective analysis of mid-regional pro-adrenomedullin

E Sozio, NA Moore, M Fabris, A Ripoli, F Rumbolo… - Respiratory …, 2022 - Springer
Abstract Background Mid-Regional pro-Adrenomedullin (MR-proADM) is an inflammatory
biomarker that improves the prognostic assessment of patients with sepsis, septic shock and …

Prognostic role of malnutrition diagnosed by bioelectrical impedance vector analysis in older adults hospitalized with COVID-19 pneumonia: a prospective study

A Da Porto, C Tascini, M Peghin, E Sozio, G Colussi… - Nutrients, 2021 - mdpi.com
Background: Little is known on the clinical relevance of the nutritional status and body
composition of patients hospitalized with SARS-CoV-2 infection. The aim of our study was to …