Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

Objective To determine the effects of low-vs. high-intensity aerobic and resistance training
on motor and cognitive function, brain activation, brain structure, and neurochemical …

The underlying pathophysiology of Parkinson's disease is complex, but mitochondrial
dysfunction has an established and prominent role. This is supported by an already large …

Parkinson's disease (PD) is a progressive neurodegenerative disorder for which only
symptomatic treatments are available. Both preclinical and clinical studies suggest that …

Abstract Objective The feature of Parkinson's disease (PD) is the heavy dopaminergic
neuron loss of substantia nigra pars compacta (SNpc), while glutaredoxin (GLRX) has been …

Neurodegeneration is among the most critical challenges that involve modern societies and
annually influences millions of patients worldwide. While the pathophysiology of Parkinson's …

Psychiatric and neurodegenerative diseases, including major depression disorder (MDD),
bipolar disorder, and Alzheimer's disease, are a burden to society. Deficits of adult …

Background Parkinson's disease (PD) is characterized by Lewy body and neurite pathology
associated with dopamine terminal dysfunction. Clinically, it is associated with motor …

Alzheimer's disease (AD) presents a significant challenge to global health. It is characterized
by progressive cognitive deterioration and increased rates of morbidity and mortality among …

Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by
memory impairment and cognitive dysfunction, which eventually leads to the disability and …