Targeting vascular (endothelial) dysfunction
A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity
Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …
Oxidative stress and endothelial dysfunction in hypertension
Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …
significant morbidity and mortality, and is becoming an increasingly common health problem …
Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function
A Daiber, F Di Lisa, M Oelze… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are associated with and/or caused by oxidative stress. This
concept has been proven by using the approach of genetic deletion of reactive species …
concept has been proven by using the approach of genetic deletion of reactive species …
Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice
Aims Epidemiological studies indicate that traffic noise increases the incidence of coronary
artery disease, hypertension and stroke. The underlying mechanisms remain largely …
artery disease, hypertension and stroke. The underlying mechanisms remain largely …
[HTML][HTML] Health position paper and redox perspectives-Disease burden by transportation noise
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …
Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction
T Münzel, C Sinning, F Post, A Warnholtz… - Annals of …, 2008 - Taylor & Francis
Endothelial dysfunction (ED) in the setting of cardiovascular risk factors such as
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …
Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertension
ND Vaziri, B Rodríguez-Iturbe - Nature clinical practice Nephrology, 2006 - nature.com
Animal studies have shown that oxidative stress and renal tubulointerstitial inflammation are
associated with, and have major roles in, the pathogenesis of hypertension. This view is …
associated with, and have major roles in, the pathogenesis of hypertension. This view is …
Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension
Endothelial dysfunction in the setting of cardiovascular risk factors such as
hypercholesterolemia, diabetes mellitus, chronic smoking, as well hypertension, is, at least …
hypercholesterolemia, diabetes mellitus, chronic smoking, as well hypertension, is, at least …
Explaining the phenomenon of nitrate tolerance
During the last century, nitroglycerin has been the most commonly used antiischemic and
antianginal agent. Unfortunately, after continuous application, its therapeutic efficacy rapidly …
antianginal agent. Unfortunately, after continuous application, its therapeutic efficacy rapidly …