[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

W Xue, W Shi, Y Kong, M Kuss, B Duan - Bioactive materials, 2021 - Elsevier
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

A bioresorbable and conductive scaffold integrating silicon membranes for peripheral nerve regeneration

P Sun, Y Guan, C Yang, H Hou, S Liu… - Advanced …, 2023 - Wiley Online Library
Peripheral nerve injury represents one of the most common types of traumatic damage,
severely impairing motor and sensory functions, and posttraumatic nerve regeneration …

High aspect ratio and light-sensitive micropillars based on a semiconducting polymer optically regulate neuronal growth

F Milos, G Tullii, F Gobbo, F Lodola… - … Applied Materials & …, 2021 - ACS Publications
Many nano-and microstructured devices capable of promoting neuronal growth and network
formation have been previously investigated. In certain cases, topographical cues have …

Current advances in biomaterials for inner ear cell regeneration

J Lu, M Wang, Y Meng, W An, X Wang, G Sun… - Frontiers in …, 2024 - frontiersin.org
Inner ear cell regeneration from stem/progenitor cells provides potential therapeutic
strategies for the restoration of sensorineural hearing loss (SNHL), however, the efficiency of …

Flexible neural interfaces based on 3D PEDOT: PSS micropillar arrays

A Lunghi, A Mariano, M Bianchi… - Advanced Materials …, 2022 - Wiley Online Library
Multi‐electrode arrays with 3D micropillars allow the recording of electrophysiological
signals in vitro with higher precision and signal‐to‐noise ratio than planar arrays. This is the …

High-aspect-ratio semiconducting polymer pillars for 3D cell cultures

G Tullii, F Giona, F Lodola, S Bonfadini… - … applied materials & …, 2019 - ACS Publications
Hybrid interfaces between living cells and nano/microstructured scaffolds have huge
application potential in biotechnology, spanning from regenerative medicine and stem cell …

[HTML][HTML] Establishment of a long-term spiral ganglion neuron culture with reduced glial cell number: Effects of AraC on cell composition and neurons

J Schwieger, KH Esser, T Lenarz, V Scheper - Journal of neuroscience …, 2016 - Elsevier
Background Sensorineural deafness is mainly caused by damage to hair cells and
degeneration of the spiral ganglion neurons (SGN). Cochlear implants can functionally …

Vertically-aligned functionalized silicon micropillars for 3D culture of human pluripotent stem cell-derived cortical progenitors

A Cutarelli, S Ghio, J Zasso, A Speccher, G Scarduelli… - Cells, 2019 - mdpi.com
Silicon is a promising material for tissue engineering since it allows to produce
micropatterned scaffolding structures resembling biological tissues. Using specific …

Strategy towards independent electrical stimulation from cochlear implants: Guided auditory neuron growth on topographically modified nanocrystalline diamond

Y Cai, F Edin, Z Jin, A Alexsson, O Gudjonsson, W Liu… - Acta biomaterialia, 2016 - Elsevier
Cochlear implants (CI) have been used for several decades to treat patients with profound
hearing loss. Nevertheless, results vary between individuals, and fine hearing is generally …

[HTML][HTML] Guided growth of auditory neurons: bioactive particles towards gapless neural–electrode interface

H Li, F Edin, H Hayashi, O Gudjonsson… - Biomaterials, 2017 - Elsevier
Cochlear implant (CI) is a successful device to restore hearing. Despite continuous
development, frequency discrimination is poor in CI users due to an anatomical gap …