Circadian rhythms and pain
The goal of this review is to provide a perspective on the nature and importance of the
relationship between the circadian and pain systems. We provide: 1) An overview of the …
relationship between the circadian and pain systems. We provide: 1) An overview of the …
Behavior-related gene regulatory networks: A new level of organization in the brain
Neuronal networks are the standard heuristic model today for describing brain activity
associated with animal behavior. Recent studies have revealed an extensive role for a …
associated with animal behavior. Recent studies have revealed an extensive role for a …
[HTML][HTML] Different neuronal activity patterns induce different gene expression programs
KM Tyssowski, NR DeStefino, JH Cho, CJ Dunn… - Neuron, 2018 - cell.com
A vast number of different neuronal activity patterns could each induce a different set of
activity-regulated genes. Mapping this coupling between activity pattern and gene induction …
activity-regulated genes. Mapping this coupling between activity pattern and gene induction …
[HTML][HTML] Enhancer histone acetylation modulates transcriptional bursting dynamics of neuronal activity-inducible genes
Neuronal activity-inducible gene transcription correlates with rapid and transient increases
in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how …
in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how …
[HTML][HTML] Evolutionarily conservative and non-conservative regulatory networks during primate interneuron development revealed by single-cell RNA and ATAC …
The differences in size and function between primate and rodent brains, and the association
of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight …
of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight …
[HTML][HTML] Neural stimulation and molecular mechanisms of plasticity and regeneration: a review
Neural stimulation modulates the depolarization of neurons, thereby triggering activity-
associated mechanisms of neuronal plasticity. Activity-associated mechanisms in turn play a …
associated mechanisms of neuronal plasticity. Activity-associated mechanisms in turn play a …
[HTML][HTML] Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum
B Nagy, A Hovhannisyan, R Barzan, TJ Chen… - PLoS …, 2017 - journals.plos.org
In the developing and adult brain, oligodendrocyte precursor cells (OPCs) are influenced by
neuronal activity: they are involved in synaptic signaling with neurons, and their proliferation …
neuronal activity: they are involved in synaptic signaling with neurons, and their proliferation …
[HTML][HTML] Synapse-to-nucleus communication through NFAT is mediated by L-type Ca2+ channel Ca2+ spike propagation to the soma
Long-term information storage in the brain requires continual modification of the neuronal
transcriptome. Synaptic inputs located hundreds of micrometers from the nucleus can …
transcriptome. Synaptic inputs located hundreds of micrometers from the nucleus can …
[HTML][HTML] Cell-type-specific patterned stimulus-independent neuronal activity in the Drosophila visual system during synapse formation
Stereotyped synaptic connections define the neural circuits of the brain. In vertebrates,
stimulus-independent activity contributes to neural circuit formation. It is unknown whether …
stimulus-independent activity contributes to neural circuit formation. It is unknown whether …
The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential
Our past experiences shape our current and future behavior. These experiences must leave
some enduring imprint on our brains, altering neural circuits that mediate behavior and …
some enduring imprint on our brains, altering neural circuits that mediate behavior and …