T-type Ca2+ channels were originally called low-voltage-activated (LVA) channels because
they can be activated by small depolarizations of the plasma membrane. In many neurons …

1. Introduction Administration Heart Failure Trial) and other trials suggest that death is
disproportionately sudden in patients with Over 2 million Americans suffer from heart failure …

At specific stages of development, nerve and muscle cells generate spontaneous electrical
activity that is required for normal maturation of intrinsic excitability and synaptic connectivity …

The process of cardiac hypertrophy is considered to involve two components: that of cardiac
myocyte (CM) enlargement and cardiac fibroblast (CF) proliferation. The interleukin‐6 (IL‐6) …

After the first demonstration 30 years ago that Ca2+ could permeate through two different
channels, the occurrence and role of T-type Ca2+ current, ICaT have been the matter of …

Transmembrane voltage-gated Ca2+ channels play a central role in the development and
control of heart contractility which is modulated by the concentration of free cytosolic calcium …

The past 5 years has witnessed an advance in our understanding of alpha1G (Ca v 3.1),
alpha1H (Ca v 3.2), and alpha1l (Ca v 3.3), the pore-forming subunits of T-type or low …

Abstract Objective: T-type Ca2+ currents (I Ca-T) are present in neonatal rat myocytes but is
not detected in adult ventricular myocytes. The present study was designed to investigate …

In cardiac hypertrophy, both excessive enlargement of cardiac myocytes (CMs) and
progressive fibrosis are known to occur simultaneously. To investigate the nature of …

In the present study the role of T-type Ca2+ channels in cancer cell proliferation was
examined. Seventeen human esophageal cancer cell lines were screened for T-type …