Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Preparation and application of dextran and its derivatives as carriers

F Chen, G Huang, H Huang - International journal of biological …, 2020 - Elsevier
As a natural and renewable biological macromolecule, dextran not only has excellent
biodegradability, but also has good biocompatibility. Dextran and its derivatives are …

[HTML][HTML] Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments

CM Tang, TO Yau, J Yu - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Chronic hepatitis B (CHB) virus infection is a global public health problem, affecting more
than 400 million people worldwide. The clinical spectrum is wide, ranging from a subclinical …

Enhanced bioavailability of nano-sized chitosan–atorvastatin conjugate after oral administration to rats

M Anwar, MH Warsi, N Mallick, S Akhter… - European journal of …, 2011 - Elsevier
A novel approach to improve the bioavailability and stability of atorvastatin (AT) was
developed by constructing a nano-sized polymer–atorvastatin conjugate. Firstly, a novel …

The application of prodrugs as a tool to enhance the properties of nucleoside reverse transcriptase inhibitors

LR Fernandes, JR Lopes, AF Bonjorno, JLB Prates… - Viruses, 2023 - mdpi.com
Antiretroviral Therapy (ART) is an effective treatment for human immunodeficiency virus
(HIV) which has transformed the highly lethal disease, acquired immunodeficiency …

Drug delivery systems in HIV pharmacotherapy: what has been done and the challenges standing ahead

A Sosnik, DA Chiappetta, ÁM Carcaboso - Journal of Controlled release, 2009 - Elsevier
Worldwide, over 40 million people are infected with the Human Immunodeficiency Virus
(HIV). The High Activity Antiretroviral Therapy (HAART) combines at least three antiretroviral …

Polymer–drug conjugates for novel molecular targets

J Sanchis, F Canal, R Lucas, MJ Vicent - Nanomedicine, 2010 - Taylor & Francis
Polymer therapeutics can be already considered as a promising field in the human
healthcare context. The discovery of the enhanced permeability and retention effect by …

Selective oxidation of 2-hydroxypropyl ethers of cellulose and dextran: Simple and efficient introduction of versatile ketone groups to polysaccharides

BLB Nichols, J Chen, P Mischnick, KJ Edgar - Biomacromolecules, 2020 - ACS Publications
Oxidation of polysaccharides has been a useful approach to new materials. However,
selectivity in oxidation of polysaccharide macromolecular polyols remains a significant …

Self‐delivery multifunctional anti‐HIV hydrogels for sustained release

J Li, X Li, Y Kuang, Y Gao, X Du… - Advanced healthcare …, 2013 - Wiley Online Library
None of the clinical trials of anti‐HIV gels based on conventional polymers or lipid emulsions
has been successful, suggesting the need of new molecular design of the anti‐HIV gels …

Influence of solvent evaporation technique parameters on diameter of submicron lamivudine-poly-ε-caprolactone conjugate particles

T Urbaniak, W Musiał - Nanomaterials, 2019 - mdpi.com
The size of active pharmaceutical ingredient carrier is one of the key properties considered
during design of submicron drug delivery systems. Particle diameter may determine drug …