The leaves from the tree Mitragyna speciosa, commonly known as Kratom, in the coffee
plant family (Rubiaceae) are commonly used in their native habitat of Southeast Asia as a …

Context The increased use of opioids has resulted in an unprecedented opioid epidemic.
Chronic opioid use causes hypogonadism, but its frequency, as well as the effects of opioids …

Background Mitragyna speciosa, referred to as “kratom”, is increasingly used in the United
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …

Kratom, a plant that produces opioid-like effects, has gained popularity in the US for self-
treating symptoms of chronic pain, mood disorders, and substance-use disorders (SUDs) …

Abstract Introduction Kratom (Mitragyna speciosa) is a tropical plant traditionally used as an
ethnomedicinal remedy for several conditions in South East Asia. Despite the increased …

Abstract Purpose of Review This work aims to provide an up-to-date review of the preclinical
and clinical scientific literature on the therapeutic value of kratom to better understand the …

Abstract Used in Southeast Asia for generations, kratom gained popularity in the United
States and elsewhere over the past several decades. Derived from Mitragyna speciosa …

Abstract Ethnopharmacological relevance Mitragyna speciosa (Korth.) is a traditional
medicinal plant widely used in Southeast Asia for its opioid-like effects. Although kratom …

Ethnopharmacological relevance The leaves of Mitragyna speciosa (Korth.) or kratom have
been traditionally used in Malaysia and Thailand mainly to enhance work productivity, as a …

Purpose This article presents updated information on kratom (Mitragyna speciosa), a natural
opioid with stimulant properties that is currently sold in the United States without a …