A tutorial: Laserspray ionization and related laser‐based ionization methods for use in mass spectrometry

S Trimpin - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This Tutorial is to provide a summary of parameters useful for successful outcomes of
laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix …

Novel ionization processes for use in mass spectrometry:'Squeezing'nonvolatile analyte ions from crystals and droplets

S Trimpin - Rapid Communications in Mass Spectrometry, 2019 - Wiley Online Library
Together with my group and collaborators, I have been fortunate to have had a key role in
the discovery of new ionization processes that we developed into new flexible, sensitive …

" Magic" ionization mass spectrometry

S Trimpin - Journal of The American Society for Mass Spectrometry, 2016 - Springer
The systematic study of the temperature and pressure dependence of matrix-assisted
ionization (MAI) led us to the discovery of the seemingly impossible, initially explained by …

Enhancing sensitivity in miniature mass spectrometry analysis via dicationic ionic liquid-based matrix-assisted ionization and charge inversion reactions

X Guo, Y Ge, H Bai, Q Ma - Green Chemistry, 2024 - pubs.rsc.org
Developing green analytical approaches has become a crucial trend in green chemistry.
These approaches encourage direct analysis to avoid any sample treatment that involves …

Suspect screening of fentanyl analogs using matrix-assisted ionization and a miniature mass spectrometer with a custom expandable mass spectral library

X Guo, Y Shang, Y Lv, H Bai, Q Ma - Analytical Chemistry, 2021 - ACS Publications
The reliable identification of fentanyl and its analogs is of great significance for public
security. However, with the growing prevalence of fentanyl compounds, current analytical …

Matrix-assisted ionization on a portable mass spectrometer: analysis directly from biological and synthetic materials

ZJ Devereaux, CA Reynolds, JL Fischer… - Analytical …, 2016 - ACS Publications
Matrix-assisted ionization (MAI)-mass spectrometry (MS) eliminates the need for high
voltage, a heat source, lasers, and compressed gases in the ionization process and uses …

Magic matrices for ionization in mass spectrometry

S Trimpin, CA Lutomski, TJ El-Baba… - International Journal of …, 2015 - Elsevier
The initial discovery that a heated inlet tube of a mass spectrometer is an ionization source
producing ions from volatile, nonvolatile, small, and large molecules with charge states …

Direct biological sample analyses by laserspray ionization miniature mass spectrometry

Y Zhai, S Liu, L Gao, L Hu, W Xu - Analytical chemistry, 2018 - ACS Publications
With improved performances, miniature mass spectrometers are becoming suitable for more
practical applications. At the same time, the coupling of an approximate ionization source is …

Vacuum matrix-assisted ionization source offering simplicity, sensitivity, and exceptional robustness in mass spectrometry

S Trimpin, M Pophristic, A Adeniji-Adele… - Analytical …, 2018 - ACS Publications
Vacuum matrix-assisted ionization (vMAI) uses select matrix compounds which when
exposed to the vacuum of a mass spectrometer produce gas-phase ions from associated …

Fifty years of desorption ionization of nonvolatile compounds

CN McEwen, BS Larsen - International Journal of Mass Spectrometry, 2015 - Elsevier
During the past 50 years mass spectrometry has advanced from a small molecule method to
one critical to understanding biological processes. The ability to analyze compounds as …