Regulatory T cells (Tregs) are key immunosuppressive cells that promote tumor growth by
hindering the effector immune response. Tregs utilize multiple suppressive mechanisms to …

Cancer stem cells (CSCs) are subpopulations of undifferentiated cancer cells within the
tumor bulk that are responsible for tumor initiation, recurrence and therapeutic resistance …

Increased levels of total tumor-infiltrating lymphocytes (TILs) are generally associated with
good prognosis in several breast cancer subtypes. Subtypes of TILs impact both tumor cells …

Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …

There are few tumor cell subpopulations with stem cell characteristics in tumor tissue,
defined as cancer stem cells (CSCs) or cancer stem-like cells (CSLCs), which can …

One of the most serious diseases affecting dairy cattle, causing significant losses both in
breeding and economy, is mastitis, an inflammation of the mammary gland. Due to the …

Heterogeneity within the tumor-infiltrating lymphocytes (TIL) population limits
immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted …

Breast cancer is the leading cause of women's death among all cancers. The main reason
associated with this is the development of metastasis and therapy-resistant breast …

Growing evidence demonstrates a strong correlation between obesity and an increased risk
of breast cancer, although the mechanisms involved have not been completely elucidated …

Lymph node metastasis has been shown to positively associated with the prognosis of many
cancers. However, in clinical treatment, lymphadenectomy is not always successful …