Background In traditional medicine whole plants or mixtures of plants are used rather than
isolated compounds. There is evidence that crude plant extracts often have greater in vitro …

Peter Winstanley here describes the pharmacology and therapeutics of the main drugs used
for falciparum malaria in the tropical setting, rather than in the developed world, as an …

Malaria is an increasing worldwide threat, with more than three hundred million infections
and one million deaths every year. The worlds poorest are the worst affected, and many treat …

We evaluated gametocyte carriage and intensities of gametocytaemia in 710 children
presenting with acute, symptomatic, uncomplicated Plasmodium falciparum malaria who …

Severe falciparum malaria, with its associated hyperpyrexia, distorts plasma levels of large
neutral amino acids (NAA) and consequently, brain uptake of individual NAA. Since brain …

Antimalarial drugs (AMs) were developed pri-marily to treat malaria; however, they can be
beneficial for many dermatological, immunological, and rheumatological diseases for which …

The risk factors associated with gametocytaemia at presentation and after treatment with
different antimalarial drug regimens were evaluated in 767 children enrolled prospectively in …

Malaria continues to be a major global health problem and seems to be increasing in some
parts of the world. By way of an introduction, relevant aspects of the disease, including …

Abstract Background Drug resistance in Plasmodium falciparum is common in many
endemic and other settings but there is no clear recommendation on when to change …

Every year, forty percent of the world population is at risk of contracting malaria. Hopes for
the erradication of this disease during the 20th century were dashed by the ability of …