Autophagy and skin wound healing

H Ren, F Zhao, Q Zhang, X Huang, Z Wang - Burns & trauma, 2022 - academic.oup.com
Autophagy is a lysosome-dependent, self-renewal mechanism that can degrade and recycle
cellular components in eukaryotic cells to maintain the stability of the intracellular …

[HTML][HTML] Copper in cancer: from pathogenesis to therapy

D Guan, L Zhao, X Shi, X Ma, Z Chen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
One of the basic trace elements for the structure and metabolism of human tissue is copper.
However, as a heavy metal, excessive intake or abnormal accumulation of copper in the …

[HTML][HTML] mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264. 7 mouse …

Q Luo, Y Song, J Kang, Y Wu, F Wu, Y Li, Q Dong… - Redox biology, 2021 - Elsevier
Copper (Cu) is a trace element necessary in animals as well as human beings. However,
excessive Cu is toxic to immunocytes, but the precise mechanism is largely unclear so far …

The role of hypoxia-inducible factor-1 alpha in multidrug-resistant breast cancer

L Yong, S Tang, H Yu, H Zhang, Y Zhang, Y Wan… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the most common cancer in women worldwide with increasing incidence.
Significant therapeutics advances in the field of breast cancer have resulted in a growing …

Biological principles of adult degenerative scoliosis

E Petrosyan, J Fares, MS Lesniak, TR Koski… - Trends in molecular …, 2023 - cell.com
The global aging population has led to an increase in geriatric diseases, including adult
degenerative scoliosis (ADS). ADS is a spinal deformity affecting adults, particularly females …

Targeting breast cancer and their stem cell population through AMPK activation: novel insights

B Uprety, H Abrahamse - Cells, 2022 - mdpi.com
Despite some significant advancements, breast cancer has become the most prevalent
cancer in the world. One of the main reasons for failure in treatment and metastasis has …

High-density lipoprotein regulates angiogenesis by affecting autophagy via miRNA-181a-5p

BA Kang, HM Li, YT Chen, MJ Deng, Y Li… - Science China Life …, 2024 - Springer
We previously demonstrated that normal high-density lipoprotein (nHDL) can promote
angiogenesis, whereas HDL from patients with coronary artery disease (dHDL) is …

Autophagy-modulated biomaterial: A robust weapon for modulating the wound environment to promote skin wound healing

J Zhang, L Li, J Yu, F Zhang, J Shi, M Li… - International Journal …, 2023 - Taylor & Francis
Autophagy, a self-renewal mechanism, can help to maintain the stability of the intracellular
environment of organisms. Autophagy can also regulate several cellular functions and is …

Autophagy plays multiple roles in the soft-tissue healing and osseointegration in dental implant surgery—a narrative review

A Ripszky Totan, MM Imre, S Parvu, D Meghea… - Materials, 2022 - mdpi.com
Dental endo-osseous implants have become a widely used treatment for replacing missing
teeth. Dental implants are placed into a surgically created osteotomy in alveolar bone, the …

Role of Tyrosine Phosphorylation in PTP–PEST

S Thirumalai Srinivasan, A Manikandan… - The Journal of …, 2024 - ACS Publications
We study the influence of tyrosine phosphorylation on PTP–PEST, a cytosolic protein
tyrosine phosphatase. Utilizing a combination of experimental data and computational …