The function of epithelial cell sheets depends on the integrity of specialized cell–cell
junctions that connect neighbouring cells. We have characterized the novel coiled-coil …

Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of
Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal …

Organ morphogenesis requires the coordinated activity of many mechanisms involved in cell
rearrangements, size control, cell proliferation and organ integrity. Here we report that …

Precise targeting and maintenance of axonal domains in myelinated axons is essential for
saltatory conduction. Caspr and Caspr2, which localize at paranodal and juxtaparanodal …

Spatial arrangement of different neuron types within a territory is essential to neuronal
development and function. How development of different neuron types is coordinated for …

Cell vertices in epithelia comprise specialized tricellular junctions (TCJs) that seal the
paracellular space between three adjoining cells [1, 2]. Although TCJs play fundamental …

Glia play crucial roles in ensheathing axons, a process that requires an intricate series of
glia-neuron interactions. The membrane-anchored protein Wrapper is present in Drosophila …

Coracle is a member of the Protein 4.1 superfamily of proteins, whose members include
Protein 4.1, the Neurofibromatosis 2 tumor suppressor Merlin, Expanded, the ERM proteins …

To identify binding partners of the A1AR (A1 adenosine receptor), yeast two-hybrid
screening of a rat embryonic cDNA library was performed. This procedure led to the …

Background A complex of three cell adhesion molecules (CAMs) Neurexin IV (Nrx IV),
Contactin (Cont) and Neuroglian (Nrg) is implicated in the formation of septate junctions …