Preoperative survival prediction in patients with glioblastoma by routine inflammatory laboratory parameters

D Pierscianek, Y Ahmadipour, A Michel… - Anticancer …, 2020 - ar.iiarjournals.org
Background: Glioblastoma (GBM) is the most common malignant brain tumor in adults and
still carries a dismal prognosis. As several studies detected a connection between …

The preoperative neutrophil-to-lymphocyte ratio predictive value for survival in patients with brain metastasis

H Picarelli, VN Yamaki, DJF Solla… - Arquivos de neuro …, 2022 - thieme-connect.com
Background The neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), platelet-to-
lymphocyte ratio (PLR), and red blood cell distribution width (RDW) have been previously …

IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells

C Dong, J Zhang, S Fang, F Liu - Cell division, 2020 - Springer
Abstract Background Recurrence of Glioblastoma multiforme (GBM) seems to be the rule
despite combination therapies. Cell invasion and cell proliferation are major reasons for …

Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers

A Vergallo, S Lista, P Lemercier, PA Chiesa… - Neurobiology of …, 2020 - Elsevier
Neuroinflammation, a key early pathomechanistic alteration of Alzheimer's disease, may
represent either a detrimental or a compensatory mechanism or both (according to the …

The clinical significance of soluble programmed cell death-ligand 1 (sPD-L1) in patients with gliomas

S Liu, Y Zhu, C Zhang, X Meng, B Sun, G Zhang… - Frontiers in …, 2020 - frontiersin.org
Background: Soluble PD-L1 (sPD-L1) in the circulation has been documented to activate
global immunosuppression and is considered a predictor of negative clinical outcomes in …

Spinal obstruction-related vs. craniocervical junction-related syringomyelia: a comparative study

C Yuan, J Guan, Y Du, Z Fang, X Wang, Q Yao… - Frontiers in …, 2022 - frontiersin.org
Background No prior reports have focused on spinal cord injury (SCI) characteristics or
inflammation after destruction of the blood–spinal cord barrier by syringomyelia. This study …

Molecular and immunologic signatures are related to clinical benefit from treatment with vocimagene amiretrorepvec (Toca 511) and 5-fluorocytosine (Toca FC) in …

WP Accomando, AR Rao, DJ Hogan, AM Newman… - Clinical Cancer …, 2020 - AACR
Abstract Purpose: High-grade gliomas (HGGs) are central nervous system tumors with poor
prognoses and limited treatment options. Vocimagene amiretrorepvec (Toca 511) is a …

Red blood cell distribution width to platelet ratio substantiates preoperative survival prediction in patients with newly-diagnosed glioblastoma

M Schneider, N Schäfer, S Apallas, AL Potthoff… - Journal of neuro …, 2021 - Springer
Object The conception of individual patient-adjusted treatment strategies is constantly
emerging in the field of neuro-oncology. Systemic laboratory markers may allow insights into …

Neutrophil-to-lymphocyte ratio is prognostic in recurrent glioblastoma multiforme treated with bevacizumab plus irinotecan

V Haksoyler, AA Besen, T Koseci, P Olgun… - Biomarkers in …, 2021 - Taylor & Francis
Aim: We intended to survey the prognostic utility of pretreatment neutrophil-to-lymphocyte
ratio (NLR) as a novel prognostic index in recurrent glioblastoma multiforme (R-GBMs) …

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

T Duraj, M Kalamian, G Zuccoli, JC Maroon… - BMC medicine, 2024 - Springer
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally
lethal prognosis despite maximal standard therapies. Here, we present a consensus …