An update on the pathogenesis of cholesterol gallstone disea... : Current Opinion in
Gastroenterology An update on the pathogenesis of cholesterol gallstone disease : Current …

Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation
where BAs exert their multiple physiological functions including stimulation of bile flow …

Cholesterol gallstone disease is a worldwide common disease. Cholesterol supersaturation
in gallbladder bile is the prerequisite for its pathogenesis, while the mechanism is not …

Despite the well-documented association between gallstones and the metabolic syndrome,,
the mechanistic links between these two disorders remain unknown. Here we show that …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Gallstone disease is very common in the Western world with an estimated prevalence of
10% to 15% in white adults, leading to significant morbidity, mortality, and considerable …

Abstract Background Liver X receptor (LXR) is an oxysterol-activated nuclear receptor
involved in the control of major metabolic pathways for cholesterol homeostasis and …

Biliary cholesterol secretion is a process important for 2 major disease complexes,
atherosclerotic cardiovascular disease and cholesterol gallstone disease. With respect to …

Background To develop a method for systematic classification of gallbladder stones, analyze
the clinical characteristics of each type of stone and provide a theoretical basis for the study …

Phase separation of cholesterol crystals from supersaturated bile is still considered the key
event in cholesterol gallstone formation. In this review, we will first provide a basal …