Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules

M Lang, A Carvalho, Z Baharoglu… - … and Molecular Biology …, 2023 - Am Soc Microbiol
Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

Optimization, purification, and structure elucidation of anthraquinone pigment derivative from Talaromyces purpureogenus as a novel promising antioxidant …

YA Hasanien, AA Nassrallah, AG Zaki… - Journal of Biotechnology, 2022 - Elsevier
This study aims to investigate the bioproduction and prospective biological applications of a
natural red pigment from Talaromyces purpureogenus AUMC2603. Maximum pigment yield …

99mTc-linezolid as a radiotracer for brain abscess: labeling, in silico docking, and biodistribution studies

OA El-Kawy, IT Ibrahim, HA Shweeta… - Applied Radiation and …, 2023 - Elsevier
Brain abscess is a life-threatening condition that requires a timely and accurate diagnosis. In
this study, linezolid, an oxazolidinone antibiotic, was labeled with technetium-99m according …

Radioiodination, nasal nanoformulation and preliminary evaluation of isovanillin: a new potential brain cancer-targeting agent

OA El-Kawy, HA Shweeta, KM Attallah - Applied Radiation and Isotopes, 2022 - Elsevier
Brain cancer is a challenging disease to treat using conventional approaches. The present
investigation aimed to develop a radiopharmaceutical targeting brain cancer based on …

Preparation and preliminary evaluation study of [131I]iodocolchicine-gallic-AuNPs: a potential scintigraphic agent for inflammation detection

BM Essa, AA Selim, OA El-Kawy… - International journal of …, 2022 - Taylor & Francis
Background Nanomedicine offers great potential for scintigraphic diagnostic imaging with
lower risk and higher quality compared to other traditional techniques. Objectives This work …