Duchenne muscular dystrophy: pathogenesis and promising therapies

M Chang, Y Cai, Z Gao, X Chen, B Liu, C Zhang… - Journal of …, 2023 - Springer
Duchenne muscular dystrophy (DMD) is a severe, progressive, muscle-wasting disease,
characterized by progressive deterioration of skeletal muscle that causes rapid loss of …

The functional role of long non-coding RNA in myogenesis and skeletal muscle atrophy

K Hitachi, M Honda, K Tsuchida - Cells, 2022 - mdpi.com
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling

H Wei, Z Xu, L Chen, Q Wei, Z Huang, G Liu, W Li… - Cell Death & …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the leading lethal malignancies and a
hypervascular tumor. Although some long non-coding RNAs (lncRNAs) have been revealed …

ATF3-activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in …

J Zhang, H Wang, H Chen, H Li, P Xu, B Liu, Q Zhang… - Autophagy, 2022 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is characterized by lung scarring and has no effective
treatment. Fibroblast-to-myofibroblast differentiation and myofibroblast proliferation and …

LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity

SH Wang, XL Zhu, F Wang, SX Chen, ZT Chen… - Cell death & …, 2021 - nature.com
Maintaining proper mitochondrial respiratory function is crucial for alleviating cardiac
metabolic disorders during obesity, and mitophagy is critically involved in this process. Long …

Upregulation of Superenhancer‐driven LncRNA FASRL by USF1 promotes de novo fatty acid biosynthesis to exacerbate hepatocellular carcinoma

JY Peng, DK Cai, RL Zeng, CY Zhang, GC Li… - Advanced …, 2023 - Wiley Online Library
Superenhancers drive abnormal gene expression in tumors and promote malignancy.
However, the relationship between superenhancer‐associated long noncoding RNA …

Lineage tracing of nuclei in skeletal myofibers uncovers distinct transcripts and interplay between myonuclear populations

C Sun, CO Swoboda, FM Morales, C Calvo… - Nature …, 2024 - nature.com
Multinucleated skeletal muscle cells need to acquire additional nuclei through fusion with
activated skeletal muscle stem cells when responding to both developmental and adaptive …

Rose long noncoding RNA lncWD83 promotes flowering by modulating ubiquitination of the floral repressor RcMYC2L

C Yeqing, L Jun, W Weinan, F Chunguo… - Plant …, 2023 - academic.oup.com
Long noncoding RNAs (lncRNAs) play important roles in various signaling pathways in
vascular plants. However, the crosstalk between lncRNAs and E3 ubiquitin ligases has been …

[HTML][HTML] Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing

H Yang, Y Zhang, Z Du, T Wu, C Yang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Skin wounds caused by diabetes are a major medical problem. Mesenchymal stem cell-
derived exosomes hold promise to quicken wound healing due to their ability to transfer …

The long non-coding RNA keratin-7 antisense acts as a new tumor suppressor to inhibit tumorigenesis and enhance apoptosis in lung and breast cancers

Z Zhao, M Meng, J Yao, H Zhou, Y Chen, J Liu… - Cell death & …, 2023 - nature.com
Expression of the long non-coding RNA (lncRNA) keratin-7 antisense (KRT7-AS) is
downregulated in various types of cancer; however, the impact of KRT7-AS deficiency on …