Background Per-and polyfluoroalkyl substances (PFAS) are of public health concern,
because of their ubiquitous and extremely persistent occurrence, and depending on their …

Polycystic ovary syndrome (PCOS) is one of the major endocrine disorders affecting women
of reproductive age. Its etiology remains unclear. It is suggested that environmental factors …

The Himalayan Sherpas, a human population of Tibetan descent, are highly adapted to life
in the hypobaric hypoxia of high altitude. Mechanisms involving enhanced tissue oxygen …

The first trimester of pregnancy ranks high in priority when minimizing harmful exposures,
given the wide-ranging types of organogenesis occurring between 4-and 12-weeks' …

Peroxisome proliferator-activated receptors (PPARα, PPAR β/δ, and PPAR γ) belong to the
transcription factor family, and they are highly expressed in all types of trophoblast during …

Inflammation is a biological response of the immune system, which can be triggered by
many factors, including pathogens. These factors may induce acute or chronic inflammation …

Concerns over the adverse reproductive outcomes in human have been raised, more
evidence including the underlying mechanism are required. Since extravillous trophoblast …

Endometrial carcinoma is the most common malignant tumor of the female genital tract in the
United States. Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor …

The unintended modulation of nuclear receptor (NR) activity by drugs can lead to toxicities
amongst the endocrine, gastrointestinal, hepatic cardiovascular, and central nervous …

Purpose This study aimed to investigate the role of miR-21 expression in the reduction of
placental function in GDM patients. Materials and Methods qRT-PCR was used to detect the …