[HTML][HTML] Redefining dilute and shoot: The evolution of the technique and its application in the analysis of foods and biological matrices by liquid chromatography mass …

B Greer, O Chevallier, B Quinn, LM Botana… - TrAC Trends in Analytical …, 2021 - Elsevier
With laboratories seeking to expand analytical capabilities and create multi-class, multi-
analyte methods, there has been a shift toward generic sample clean-up techniques such as …

[HTML][HTML] From fundamentals in calibration to modern methodologies: a tutorial for small molecules quantification in liquid chromatography–mass spectrometry …

G Visconti, J Boccard, M Feinberg, S Rudaz - Analytica chimica acta, 2023 - Elsevier
Over the last two decades, liquid chromatography coupled to mass-spectrometry (LC‒MS)
has become the gold standard to perform qualitative and quantitative analyses of small …

[HTML][HTML] Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research

A Sens, S Rischke, L Hahnefeld, E Dorochow… - Journal of Mass …, 2023 - Elsevier
The emerging disciplines of lipidomics and metabolomics show great potential for the
discovery of diagnostic biomarkers, but appropriate pre-analytical sample-handling …

[HTML][HTML] Simultaneous quantification of steroid hormones and endocannabinoids (ECs) in human hair using an automated supported liquid extraction (SLE) and LC …

CD Voegel, MR Baumgartner, T Kraemer, S Wüst… - Talanta, 2021 - Elsevier
Endogenous steroid hormones and endocannabinoids (ECs) are important regulators in the
stress response of the human body. For the measurement of chronic stress, hair analysis …

[HTML][HTML] Straightforward quantification of endogenous steroids with liquid chromatography–tandem mass spectrometry: Comparing calibration approaches

G Visconti, M De Figueiredo, O Salamin… - … of Chromatography B, 2023 - Elsevier
Different calibration strategies are used in liquid chromatography hyphenated to mass
spectrometry (LC-MS) bioanalysis. Currently, the surrogate matrix and surrogate analyte …

Simultaneous quantification of endocannabinoids, oleoylethanolamide and steroid hormones in human plasma and saliva

LJ Ney, KL Felmingham, R Bruno, A Matthews… - … of Chromatography B, 2020 - Elsevier
Endogenous cannabinoids are an increasingly intriguing target for biological research,
given the changing legal status of medicinal cannabinoid-based products throughout the …

[HTML][HTML] Endocannabinoid analysis in GlucoEXACT plasma: Method validation and sample handling recommendations

A Sens, D Thomas, SMG Schäfer, A König, A Pinter… - Talanta, 2024 - Elsevier
Endocannabinoids (ECs), such as anandamide and 2-arachidonyl glycerol (2-AG),
contribute to the pathology of inflammatory, malignant, cardiovascular, metabolic and mental …

Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer

M Kienzl, C Hasenoehrl, K Maitz… - …, 2021 - Taylor & Francis
Monoacylglycerol lipase (MGL) expressed in cancer cells influences cancer pathogenesis
but the role of MGL in the tumor microenvironment (TME) is less known. Using a syngeneic …

Implementation of lipidomics in clinical routine: Can fluoride/citrate blood sampling tubes improve preanalytical stability?

L Hahnefeld, R Gurke, D Thomas, Y Schreiber… - Talanta, 2020 - Elsevier
The impact of preanalytical sample handling on lipid stability has been assessed in human
plasma using targeted LC-MS/MS quantification of endocannabinoids, sphingolipids and …

[HTML][HTML] Tumor microenvironment-derived monoacylglycerol lipase provokes tumor-specific immune responses and lipid profiles

E Gruden, M Kienzl, C Hasenoehrl… - … and Essential Fatty …, 2023 - Elsevier
We recently described that monoacylglycerol lipase (MGL) is present in the tumor
microenvironment (TME), increasing tumor growth. In this study we compare the implications …