Over the last two decades, liquid chromatography coupled to mass-spectrometry (LC‒MS) has become the gold standard to perform qualitative and quantitative analyses of small …
A Sens, S Rischke, L Hahnefeld, E Dorochow… - Journal of Mass …, 2023 - Elsevier
The emerging disciplines of lipidomics and metabolomics show great potential for the discovery of diagnostic biomarkers, but appropriate pre-analytical sample-handling …
CD Voegel, MR Baumgartner, T Kraemer, S Wüst… - Talanta, 2021 - Elsevier
Endogenous steroid hormones and endocannabinoids (ECs) are important regulators in the stress response of the human body. For the measurement of chronic stress, hair analysis …
Different calibration strategies are used in liquid chromatography hyphenated to mass spectrometry (LC-MS) bioanalysis. Currently, the surrogate matrix and surrogate analyte …
Endogenous cannabinoids are an increasingly intriguing target for biological research, given the changing legal status of medicinal cannabinoid-based products throughout the …
A Sens, D Thomas, SMG Schäfer, A König, A Pinter… - Talanta, 2024 - Elsevier
Endocannabinoids (ECs), such as anandamide and 2-arachidonyl glycerol (2-AG), contribute to the pathology of inflammatory, malignant, cardiovascular, metabolic and mental …
M Kienzl, C Hasenoehrl, K Maitz… - …, 2021 - Taylor & Francis
Monoacylglycerol lipase (MGL) expressed in cancer cells influences cancer pathogenesis but the role of MGL in the tumor microenvironment (TME) is less known. Using a syngeneic …
L Hahnefeld, R Gurke, D Thomas, Y Schreiber… - Talanta, 2020 - Elsevier
The impact of preanalytical sample handling on lipid stability has been assessed in human plasma using targeted LC-MS/MS quantification of endocannabinoids, sphingolipids and …
E Gruden, M Kienzl, C Hasenoehrl… - … and Essential Fatty …, 2023 - Elsevier
We recently described that monoacylglycerol lipase (MGL) is present in the tumor microenvironment (TME), increasing tumor growth. In this study we compare the implications …