Revolutionizing medicinal chemistry: the application of artificial intelligence (AI) in early drug discovery

R Han, H Yoon, G Kim, H Lee, Y Lee - Pharmaceuticals, 2023 - mdpi.com
Artificial intelligence (AI) has permeated various sectors, including the pharmaceutical
industry and research, where it has been utilized to efficiently identify new chemical entities …

Applications of machine learning to identify and characterize the sounds produced by fish

VR Barroso, FC Xavier… - ICES Journal of Marine …, 2023 - academic.oup.com
Aquatic ecosystems are constantly changing due to anthropic stressors, which can lead to
biodiversity loss. Ocean sound is considered an essential ocean variable, with the potential …

StackPDB: predicting DNA-binding proteins based on XGB-RFE feature optimization and stacked ensemble classifier

Q Zhang, P Liu, X Wang, Y Zhang, Y Han, B Yu - Applied Soft Computing, 2021 - Elsevier
DNA-binding proteins (DBPs) not only play an important role in all aspects of genetic
activities such as DNA replication, recombination, repair, and modification but also are used …

Motion Sensor–Based Fall Prevention for Senior Care: A Hidden Markov Model with Generative Adversarial Network Approach

S Yu, Y Chai, S Samtani, H Liu… - Information Systems …, 2024 - pubsonline.informs.org
Whereas modern medicine has enabled humans to live longer and more robust lives, recent
years have seen a significant increase in chronic care costs. The prevention of threats to …

A new algorithm to train hidden Markov models for biological sequences with partial labels

J Li, JY Lee, L Liao - BMC bioinformatics, 2021 - Springer
Abstract Background Hidden Markov models (HMM) are a powerful tool for analyzing
biological sequences in a wide variety of applications, from profiling functional protein …

Significant non-existence of sequences in genomes and proteomes

G Koulouras, MC Frith - Nucleic acids research, 2021 - academic.oup.com
Minimal absent words (MAWs) are minimal-length oligomers absent from a genome or
proteome. Although some artificially synthesized MAWs have deleterious effects, there is still …

A dual-channel semi-supervised learning framework on graphs via knowledge transfer and meta-learning

Z Qiao, P Wang, P Wang, Z Ning, Y Fu, Y Du… - ACM Transactions on …, 2024 - dl.acm.org
This article studies the problem of semi-supervised learning on graphs, which aims to
incorporate ubiquitous unlabeled knowledge (eg, graph topology, node attributes) with few …

Real-time assembly support system with hidden markov model and hybrid extensions

A Gellert, SA Precup, A Matei, BC Pirvu, CB Zamfirescu - Mathematics, 2022 - mdpi.com
This paper presents a context-aware adaptive assembly assistance system meant to support
factory workers by embedding predictive capabilities. The research is focused on the …

[HTML][HTML] Review of Machine Learning solutions for Eating Disorders

S Ghosh, P Burger, M Simeunovic, J Maas… - International Journal of …, 2024 - Elsevier
Abstract Background Eating Disorders (EDs) are one of the most complex psychiatric
disorders, with significant impairment of psychological and physical health, and …

Developing sustainable classification of diseases via deep learning and semi-supervised learning

C Yin, Z Chen - Healthcare, 2020 - mdpi.com
Disease classification based on machine learning has become a crucial research topic in
the fields of genetics and molecular biology. Generally, disease classification involves a …