Cancer neuroscience: State of the field, emerging directions

F Winkler, HS Venkatesh, M Amit, T Batchelor, IE Demir… - Cell, 2023 - cell.com
The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

The neuroscience of cancer

R Mancusi, M Monje - Nature, 2023 - nature.com
The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Haematopoietic stem cell activity and interactions with the niche

S Pinho, PS Frenette - Nature reviews Molecular cell biology, 2019 - nature.com
The haematopoietic stem cell (HSC) microenvironment in the bone marrow, termed the
niche, ensures haematopoietic homeostasis by controlling the proliferation, self-renewal …

[HTML][HTML] Cellular and functional heterogeneity of the airway epithelium

JD Davis, TP Wypych - Mucosal immunology, 2021 - Elsevier
The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Nerves in cancer

AH Zahalka, PS Frenette - Nature Reviews Cancer, 2020 - nature.com
The contribution of nerves to the pathogenesis of malignancies has emerged as an
important component of the tumour microenvironment. Recent studies have shown that …

Olfactory sensory experience regulates gliomagenesis via neuronal IGF1

P Chen, W Wang, R Liu, J Lyu, L Zhang, B Li, B Qiu… - Nature, 2022 - nature.com
Animals constantly receive various sensory stimuli, such as odours, sounds, light and touch,
from the surrounding environment. These sensory inputs are essential for animals to search …

Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

A metabolite-triggered tuft cell-ILC2 circuit drives small intestinal remodeling

C Schneider, CE O'Leary, J von Moltke, HE Liang… - Cell, 2018 - cell.com
The small intestinal tuft cell-ILC2 circuit mediates epithelial responses to intestinal helminths
and protists by tuft cell chemosensory-like sensing and IL-25-mediated activation of lamina …

RETRACTED ARTICLE: Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

A Kamiya, Y Hayama, S Kato, A Shimomura… - Nature …, 2019 - nature.com
The effects of autonomic innervation of tumors on tumor growth remain unclear. Here we
developed a series of genetic techniques to manipulate autonomic innervation in a tumor …