The obesity epidemic is a global issue and shows no signs of abating, while the cause of
this epidemic remains unclear. Marketing practices of energy-dense foods and institutionally …

Over 35 years of research suggests that endogenous hypothalamic serotonin (5-
hydroxytryptamine) plays an important part in within-meal satiation and post-meal satiety …

The pivotal role of 5-HT in the control of appetite was formally proposed nearly 30 years ago.
In particular endogenous hypothalamic 5-HT has been implicated in the processes of within …

Rationale Many studies support the validity of the chronic mild stress (CMS) model of
depression in rodents. However, most of them focus on analysis of reactivity to rewards …

The attenuation of food intake as induced by an increase in serotonergic (5‐
hydroxytryptamine, 5‐HT) efficacy has been a target of antiobesity pharmacotherapies …

Controlled/sustained delivery systems have been developed rapidly which show the ability
to overcome the obstacles of traditional delivery systems. Daily development of biomedical …

Background Posttraumatic stress disorder (PTSD) is a very debilitating disease refractory to
current treatment with selective serotonin reuptake inhibitors (SSRIs) in up to 30 percent of …

Abstract Background 4− 20% of people report using cannabis during pregnancy, thereby it is
essential to assess the associated risks. There is some evidence that prenatal cannabis …

We tested the hypothesis that, for rats fed a high-fat diet (HFD), a prioritization of maintaining
protein intake may increase energy consumption and hence result in obesity, particularly for …

The serotonin and noradrenaline reuptake inhibitor sibutramine has been licensed as an
anti-obesity treatment for more than a decade. However, while inhibitory effects on food …