Background Cardiovascular disease is one of the most concerning chronic diseases in the
world. Many studies have shown that platelet overactivation is a very important factor in the …

Platelets are small anucleated cells that constantly patrol the cardiovascular system to
preserve its integrity and prevent excessive blood loss where the vessel lining is breached …

Procoagulant platelets are a subtype of activated platelets that sustains thrombin generation
in order to consolidate the clot and stop bleeding. This aspect of platelet activation is gaining …

Abstract Ethnopharmacological relevance The leeches (Shuizhi) comprise approximately
680 species distributed throughout the world. As recorded, they have been used as …

The interaction of platelet agonists with their respective membrane receptors triggers
intracellular signaling, among which cytosolic ion fluxes play an important role in activation …

Aims Platelets retain cytoplasmic messenger RNA and are capable of protein biosynthesis.
Several diseases are known to impact the platelet transcriptome but the effect of non …

Increasing evidence has shown that collagen peptides had various biological activities. In
this study, a novel antiplatelet peptide Met‐Glu (ME) was separated and identified from silver …

A rise in cytosolic calcium concentration ([Ca 2+] cyt) is central to platelet activation. Agonists
stimulate a rise in [Ca 2+] cyt through a combination of Ca 2+ release from intracellular …

Acute coronary syndrome (ACS) is associated with sudden, reduced blood flow to the heart
and usually correlated with coronary thrombosis [1]. Therefore, platelets play an important …

Zinc (Zn2+) is an essential trace element which regulates intracellular processes in multiple
cell types. Whilst Zn2+ has been shown to be released from intracellular compartments of a …