Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Hybrid biomimetic nanovesicles to drive high lung biodistribution and prevent cytokine storm for ARDS treatment

Q Qiao, X Liu, K Cui, X Li, T Tian, Y Yu, B Niu, L Kong… - ACS …, 2022 - ACS Publications
Acute respiratory distress syndrome (ARDS) has been a life threat for patients in ICUs. Vast
efforts have been devoted, while no medication has proved viable, which may be ascribed to …

Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS)

Q Huang, Y Le, S Li, Y Bian - Respiratory Research, 2024 - Springer
Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …

Hexahydrocurcumin from Zingiberis rhizoma attenuates lipopolysaccharide-induced acute pneumonia through JAK1/STAT3 signaling pathway

R Li, Q Liang, Q Yang, W Dai, Y Xiao, H Pan, Z Zhang… - Phytomedicine, 2024 - Elsevier
Background Pneumonia is one of the major causes of death after pathogens infection.
Zingiberis rhizoma (GAN JIANG) is a herb that used in combination with other Chinese …

[HTML][HTML] Albumin-based formononetin nanomedicines for lung injury and fibrosis therapy via blocking macrophage pyroptosis

B Ouyang, L Deng, F Yang, H Shi, N Wang, W Tang… - Materials Today Bio, 2023 - Elsevier
Pulmonary fibrosis that occurs following lung injury is a progressive and fatal disease since
continual damage to lung tissue triggers the dysregulated inflammation response and …

Emerging application of nanomedicine-based therapy in acute respiratory distress syndrome

Y Xu, L Lv, Q Wang, Q Yao, L Kou, H Zhang - Colloids and Surfaces B …, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

A Chromium-Based magnetic resonance probe for in situ gastric pH imaging

Y Xu, W Yang, Z Wu, H Wang, T Cui, W Zeng… - Chemical Engineering …, 2024 - Elsevier
Effective monitoring of gastric fluid pH is crucial for diagnosing gastric diseases and
evaluating anti-gastric-acid therapies. The invasiveness and low patient compliance with …

Precise nanodrug delivery systems with cell-specific targeting for ALI/ARDS treatment

P Lin, R Gao, Z Fang, W Yang, Z Tang, Q Wang… - International journal of …, 2023 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common acute
and critical diseases in clinics and have no effective treatment to date. With the concept of …

[HTML][HTML] Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory …

B Yang, W Luo, M Wang, Y Tang, W Zhu, L Jin… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Activation of the innate immune system through toll-like receptors (TLRs) has been
repeatedly demonstrated in non-alcoholic fatty liver disease (NAFLD) and several TLRs …