Genetics of gastric cancer
MH McLean, EM El-Omar - Nature reviews Gastroenterology & …, 2014 - nature.com
Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …
[HTML][HTML] A review on development of MUC1-based cancer vaccine
T Gao, Q Cen, H Lei - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Abstract Mucin 1 (MUC1) is a transmembrane mucin glycoprotein expressed on the surface
of almost all epithelial cells. Aberrantly glycosylated MUC1 is associated with cellular …
of almost all epithelial cells. Aberrantly glycosylated MUC1 is associated with cellular …
The mucin family of proteins: candidates as potential biomarkers for colon cancer
Simple Summary Colorectal cancer is the second leading cause of cancer-related deaths in
the United States with an overall 5-year survival of 65%. While there have been many …
the United States with an overall 5-year survival of 65%. While there have been many …
Dual assaying of breast cancer biomarkers by using a sandwich–type electrochemical aptasensor based on a gold nanoparticles–3D graphene hydrogel …
Z Shekari, HR Zare, A Falahati - Sensors and Actuators B: Chemical, 2021 - Elsevier
The present study was conducted to fabricate a sandwich–type electrochemical aptasensor
for the simultaneous determination of two important biomarkers in breast cancer, namely …
for the simultaneous determination of two important biomarkers in breast cancer, namely …
Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor–positive (HR+)/HER2-negative metastatic breast cancer
AA Davis, J Luo, T Zheng, C Dai, X Dong, L Tan… - Clinical Cancer …, 2023 - AACR
Purpose: Clinical biomarkers to identify patients unlikely to benefit from CDK4/6 inhibition
(CDK4/6 i) in combination with endocrine therapy (ET) are lacking. We implemented a …
(CDK4/6 i) in combination with endocrine therapy (ET) are lacking. We implemented a …
The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker
ML Salmans, F Zhao, B Andersen - Breast Cancer Research, 2013 - Springer
Initially discovered as an estrogen-responsive gene in breast cancer cell lines, anterior
gradient 2 (AGR2) is a developmentally regulated gene belonging to the protein disulfide …
gradient 2 (AGR2) is a developmentally regulated gene belonging to the protein disulfide …
MUC1 (CD227): a multi-tasked molecule
V Apostolopoulos, L Stojanovska… - Cellular and molecular life …, 2015 - Springer
Abstract Mucin 1 (MUC1 [CD227]) is a high-molecular weight (> 400 kDa), type I membrane-
tethered glycoprotein that is expressed on epithelial cells and extends far above the …
tethered glycoprotein that is expressed on epithelial cells and extends far above the …
MUC15 inhibits dimerization of EGFR and PI3K–AKT signaling and is associated with aggressive hepatocellular carcinomas in patients
Background & Aims Aberrant expression of MUC15 correlates with development of
colorectal adenocarcinoma, and MUC15 has been reported to prevent trophoblast invasion …
colorectal adenocarcinoma, and MUC15 has been reported to prevent trophoblast invasion …
Pathobiological implications of mucin glycans in cancer: Sweet poison and novel targets
Mucins are large glycoproteins expressed on the epithelia that provide a protective barrier
against harsh insults from toxins and pathogenic microbes. These glycoproteins are …
against harsh insults from toxins and pathogenic microbes. These glycoproteins are …
Highly sensitive and specific colorimetric detection of cancer cells via dual-aptamer target binding strategy
Simple, rapid, sensitive and specific detection of cancer cells is of great importance for early
and accurate cancer diagnostics and therapy. By coupling nanotechnology and dual …
and accurate cancer diagnostics and therapy. By coupling nanotechnology and dual …