With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Drugs bind to their target proteins, which interact with downstream effectors and ultimately
perturb the transcriptome of a cancer cell. These perturbations reveal information about their …

The increasing prevalence of obesity worldwide is associated with an increased risk of
various diseases, including multiple metabolic diseases, cardiovascular diseases, and …

Fatty acid binding proteins (FABPs) are small, water soluble proteins that bind long chain
fatty acids and other biologically active ligands to facilitate intracellular localization. Twelve …

Highlights•Fatty acid binding protein 5 (FABP5) is upregulated in many cancers, particularly
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …

The adipose tissue microenvironment plays a key role in tumour initiation and progression
because it provides fatty acids and adipokines to tumour cells. The fatty acid-binding protein …

Obesity, a pandemic disease, is caused by an excessive accumulation of fat that can have
detrimental effects on health. Adipose tissue plays a very important endocrine role, secreting …

This review focuses on primary cultures of human prostatic epithelial cells and their
applications as models of normal and malignant biological behavior. Current abilities to …

Currently, there is renewed interest in elucidating the metabolic characteristics of cancer and
how these characteristics may be exploited as therapeutic targets. Much attention has …