Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …

Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the
excessive generation or accumulation of free radicals or their oxidation products. Free …

Proteins of the interleukin-6 (IL-6) family bind to receptors in the plasma membrane.
Subsequent signal transduction involves activation of the janus kinase (JAK) and signal …

Myocardial infarction triggers an inflammatory cascade that results in healing and
replacement of the damaged tissue with scar. Cardiomyocyte necrosis triggers innate …

Objective: The proinflammatory cytokines interleukin (IL)-1β and IL-6 are supposed to be
involved in various cardiovascular diseases including reperfusion injury and cardiac …

Circulating levels of interleukin (IL)–6 and related cytokines are elevated in patients with
congestive heart failure and after myocardial infarction. Serum IL-6 concentrations are …

The nervous system and cardiovascular system develop in concert and are functionally
interconnected in both health and disease. This white paper focuses on the cellular and …

Cardiac hypertrophy entails complex structural remodeling involving rearrangement of
muscle fibers, interstitial fibrosis, accumulation of extracellular matrix, and angiogenesis …

Background—Nitric oxide (NO) synthesized within sinoatrial cells recently has been shown
to participate in the autonomic control of heart rate. We hypothesized that NO in the neuronal …

Biomarkers such as interleukin-6 (IL-6), soluble interleukin-6 receptor (sIL-6R), and high
sensitive C-reactive protein (hsCRP) have been reported to be elevated in acute myocardial …