Epigenome-wide association studies: current knowledge, strategies and recommendations

MP Campagna, A Xavier, J Lechner-Scott, V Maltby… - Clinical …, 2021 - Springer
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …

Ten years of EWAS

S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Database resources of the national genomics data center, China national center for bioinformation in 2022

Nucleic Acids Research, 2022 - academic.oup.com
Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global research …

Database resources of the national genomics data center, China national center for bioinformation in 2023

Nucleic acids research, 2023 - academic.oup.com
Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global academic …

Genome Warehouse: a public repository housing genome-scale data

M Chen, Y Ma, S Wu, X Zheng, H Kang… - Genomics …, 2021 - academic.oup.com
Abstract The Genome Warehouse (GWH) is a public repository housing genome assembly
data for a wide range of species and delivering a series of web services for genome data …

Database resources of the national genomics data center in 2020

Nucleic acids research, 2020 - academic.oup.com
Abstract The National Genomics Data Center (NGDC) provides a suite of database
resources to support worldwide research activities in both academia and industry. With the …

EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study

Z Xiong, F Yang, M Li, Y Ma, W Zhao… - Nucleic Acids …, 2022 - academic.oup.com
Abstract Epigenome-Wide Association Study (EWAS) has become a standard strategy to
discover DNA methylation variation of different phenotypes. Since 2018, we have developed …

Diversity in EWAS: current state, challenges, and solutions

CE Breeze, JYY Wong, S Beck, SI Berndt… - Genome Medicine, 2022 - Springer
Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA
methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and …

[HTML][HTML] Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related …

A Urban, D Sidorenko, D Zagirova, E Kozlova… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Aging is a complex and multifactorial process that increases the risk of various age-related
diseases and there are many aging clocks that can accurately predict chronological age …

mLiftOver: harmonizing data across Infinium DNA methylation platforms

BH Chen, W Zhou - Bioinformatics, 2024 - academic.oup.com
Abstract Motivation Infinium DNA methylation BeadChips are widely used for genome-wide
DNA methylation profiling at the population scale. Recent updates to probe content and …