Disclaimer: This statement is designed primarily as an educational resource for medical
geneticists and other clinicians to help them provide quality medical services. Adherence to …

Genetic testing is associated with many ethical challenges on the individual, organizational
and macro level of health care systems. The provision of genetic testing for rare diseases in …

BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

Importance A targeted genomic sequencing platform focused on diseases presenting in the
first year of life may minimize financial and ethical challenges associated with rapid whole …

The genetic basis for more than 2 dozen monogenic dyslipidemias has largely been
defined. Genetic technologies, such as DNA sequencing, can detect both rare and common …

Background Data on the modalities of disclosing genomic secondary findings (SFs) remain
scarce. We explore cancer patients' and the general public's perspectives about disclosing …

In paediatric oncology, genomics raises new ethical, legal and psychological issues, as
somatic and constitutional situations intersect throughout the care pathway. The discovery of …

Purpose Patients undergoing clinical exome sequencing (ES) are routinely offered the
option to receive secondary findings (SF). However, little is known about the views of …

In pediatric oncology, genetic and genomic tests are proposed throughout the care pathway
for many reasons (eg, cancer characterization, identification of the most appropriate …

Whole-genome sequencing (WGS) is being used in research and clinical settings in cancer
genomics. Studies show that cancer patients generally have positive attitudes toward tumor …