Cerebral edema formation after stroke: emphasis on blood–brain barrier and the lymphatic drainage system of the brain

S Chen, L Shao, L Ma - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …

Immune Response in Traumatic Brain Injury

E Cáceres, JC Olivella, M Di Napoli… - Current Neurology and …, 2024 - Springer
Abstract Purpose of Review This review aims to comprehensively examine the immune
response following traumatic brain injury (TBI) and how its disruption can impact healing …

[HTML][HTML] Neuroanatomy, amygdala

Q AbuHasan, V Reddy, W Siddiqui - 2019 - europepmc.org
The limbic system is vital for one's normal functioning. This system acts as the center of
emotions, behavior, and memory. It is also a contributor to the control of reactions to stress …

Identifying delay in glymphatic clearance of labeled protons post-acute head trauma utilizing 3D ASL MRI (arterial spin labeling): A pilot study

CR Joseph, JK Lim, BN Grohol, M Zivcevska… - Scientific Reports, 2024 - nature.com
This study correlated mild traumatic brain injury (mTBI) cognitive changes with ASL-MRI
glymphatic clearance rates (GCRs) and recovery with GCR improvement. mTBI disrupts the …

[HTML][HTML] Neuroanatomy, hypothalamus

MH Bear, V Reddy, PC Bollu - StatPearls [internet], 2022 - ncbi.nlm.nih.gov
Landmarks defining the regions of the hypothalamus include the lamina terminalis, pituitary
gland, mammillary bodies, and superior hypothalamic sulcus (see Figure. The …

Theiler's virus-mediated immunopathology in the CNS and heart: roles of organ-specific cytokine and lymphatic responses

S Omura, E Kawai, F Sato, NE Martinez… - Frontiers in …, 2018 - frontiersin.org
Theiler's murine encephalomyelitis virus (TMEV) induces different diseases in the central
nervous system (CNS) and heart, depending on the mouse strains and time course, with …

Xueshuantong improves functions of lymphatic ducts and modulates inflammatory responses in Alzheimer's disease mice

R Zheng, Y Huang, Q Zhou - Frontiers in pharmacology, 2021 - frontiersin.org
Recent studies have revealed significant contributions of lymphatic vessels (LVs) to vital
functions of the brain, especially related to clearance of waste from the brain and immune …

Follicular dendritic cells of lymph nodes as human immunodeficiency virus/simian immunodeficiency virus reservoirs and insights on cervical lymph node

RS Dave, P Jain, SN Byrareddy - Frontiers in immunology, 2018 - frontiersin.org
A hallmark feature of follicular dendritic cells (FDCs) within the lymph nodes (LNs) is their
ability to retain antigens and virions for a prolonged duration. FDCs in the cervical lymph …

New Insights on Mechanisms and Therapeutic Targets of Cerebral Edema

P Shang, R Zheng, K Wu, C Yuan… - Current …, 2024 - benthamdirect.com
Cerebral Edema (CE) is the final common pathway of brain death. In severe neurological
disease, neuronal cell damage first contributes to tissue edema, and then Increased …

[HTML][HTML] Meningeal lymphatics in aging and Alzheimer's disease

RJ Jaffe, RS Dave, SN Byrareddy - Annals of Translational …, 2019 - ncbi.nlm.nih.gov
Recent research from the Kipnis laboratory (1-3) has highlighted the significance of
meningeal lymphatics, which were originally identified in the dura mater of rat (4). These …