[HTML][HTML] Pushing the Frontiers: Optogenetics for Illuminating the Neural Pathophysiology of Bipolar Disorder

L Kong, X Guo, Y Shen, L Xu, H Huang… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Bipolar disorder (BD), a disabling mental disorder, is featured by the oscillation between
episodes of depression and mania, along with disturbance in the biological rhythms. It is on …

Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control

M Bandarabadi, S Li, L Aeschlimann, G Colombo… - Molecular …, 2024 - nature.com
Abstract Hypocretin/Orexin (HCRT/OX) and dopamine (DA) are both key effectors of
salience processing, reward and stress-related behaviors and motivational states, yet their …

[HTML][HTML] The role of subicular VIP-expressing interneurons on seizure dynamics in the intrahippocampal kainic acid model of temporal lobe epilepsy

S Rahimi, P Salami, P Matulewicz, A Schmuck… - Experimental …, 2023 - Elsevier
The subiculum, a key output region of the hippocampus, is increasingly recognized as
playing a crucial role in seizure initiation and spread. The subiculum consists of …

Role of vesicular monoamine transporter-2 for treating attention deficit hyperactivity disorder: a review

H Warlick IV, D Tocci, S Prashar, E Boldt, A Khalil… - …, 2024 - Springer
Abstract Rationale The Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition)
classifies attention deficit hyperactivity disorder (ADHD) as a neurodevelopmental disorder …

Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3

M Zupančič, E Keimpema, EO Tretiakov… - Nature …, 2024 - nature.com
Acquisition of specialized cellular features is controlled by the ordered expression of
transcription factors (TFs) along differentiation trajectories. Here, we find a member of the …

STORM imaging buffer with a refractive index matched to standard immersion oil

Y Lee, Y Lee, M Lee, D Koo, D Kim, H Kim, K Lee… - ACS …, 2023 - ACS Publications
Stochastic optical reconstruction microscopy (STORM) provides exceptional super-
resolution imaging by sparsely blinking individual dye molecules in thiol-containing media …

Brain‐wide mapping of efferent projections of glutamatergic (Onecut3+) neurons in the lateral mouse hypothalamus

M Zupančič, E Tretiakov, Z Máté, F Erdélyi… - Acta …, 2023 - Wiley Online Library
Aim This study mapped the spatiotemporal positions and connectivity of Onecut3+ neuronal
populations in the developing and adult mouse brain. Methods We generated fluorescent …

Anterior cingulate cortex contributes to the hyperlocomotion under nitrogen narcosis

B Peng, XB Wu, ZJ Zhang, D Cao, LX Zhao, H Wu… - Neuroscience …, 2024 - Springer
Nitrogen narcosis is a neurological syndrome that manifests when humans or animals
encounter hyperbaric nitrogen, resulting in a range of motor, emotional, and cognitive …

Unveiling Hypothalamic Molecular Signatures via Retrograde Viral Tracing and Single-Cell Transcriptomics

M Junaid, HK Choe, K Kondoh, EJ Lee, SB Lim - Scientific Data, 2023 - nature.com
Despite the importance of hypothalamic neurocircuits in regulating homeostatic and survival-
related behaviors, our understanding of the intrinsic molecular identities of neural …

Modulation of Hypothalamic Dopamine Neuron Activity by Interaction Between Caloric State and Amphetamine in Zebrafish Larvae

P Bansal, MF Roitman, EE Jung - Journal of Neuroscience …, 2024 - Wiley Online Library
Dopamine (DA) signaling is evoked by both food and drugs that humans come to abuse.
Moreover, physiological state (eg, hunger versus satiety) can modulate the response …