Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes

NJ Hogrebe, M Ishahak, JR Millman - Cell Stem Cell, 2023 - cell.com
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Tailoring gelation mechanisms for advanced hydrogel applications

V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

Improving chronic diabetic wound healing through an injectable and self-healing hydrogel with platelet-rich plasma release

Z Qian, H Wang, Y Bai, Y Wang, L Tao… - … applied materials & …, 2020 - ACS Publications
Diabetic skin ulcer is one of the severe complications of diabetes mellitus, which has a high
incidence and may cause death or disability. Platelet-rich plasma (PRP) is widely used in …

An adhesive hydrogel with “Load‐Sharing” effect as tissue bandages for drug and cell delivery

J Chen, D Wang, LH Wang, W Liu, A Chiu… - Advanced …, 2020 - Wiley Online Library
Hydrogels with adhesive properties have potential for numerous biomedical applications.
Here, the design of a novel, intrinsically adhesive hydrogel and its use in developing internal …

Hydrogel: Diversity of structures and applications in food science

J Li, X Jia, L Yin - Food Reviews International, 2021 - Taylor & Francis
Hydrogels are a series of soft and wet materials with three dimensions of crosslinked
networks. Hydrogels have attracted great attention due to their diverse functional properties …

Covalent organic frameworks for biomedical applications

A Esrafili, A Wagner, S Inamdar… - Advanced Healthcare …, 2021 - Wiley Online Library
Covalent organic frameworks (COFs) are porous organic polymeric materials that are
composed of organic elements and linked together by the thermodynamically stable …

A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes

X Wang, KG Maxwell, K Wang, DT Bowers… - Science translational …, 2021 - science.org
Transplantation of stem cell–derived β (SC-β) cells represents a promising therapy for type 1
diabetes (T1D). However, the delivery, maintenance, and retrieval of these cells remain a …

Advances in pancreatic islet transplantation sites for the treatment of diabetes

F Cayabyab, LR Nih, E Yoshihara - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetes is a complex disease that affects over 400 million people worldwide. The life-long
insulin injections and continuous blood glucose monitoring required in type 1 diabetes …

Hydrogels in emerging technologies for type 1 diabetes

S Fuchs, AU Ernst, LH Wang, K Shariati… - Chemical …, 2020 - ACS Publications
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …