Methods for extracting genomic DNA from whole blood samples: current perspectives

D Chacon-Cortes, LR Griffiths - Journal of Biorepository Science for …, 2014 - Taylor & Francis
Deoxyribonucleic acid (DNA) extraction has considerably evolved since it was initially
performed back in 1869. It is the first step required for many of the available downstream …

Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer

NL Burdett, MO Willis, K Alsop, AL Hunt, A Pandey… - Nature …, 2023 - nature.com
High-grade serous ovarian cancer (HGSC) is frequently characterized by homologous
recombination (HR) DNA repair deficiency and, while most such tumors are sensitive to …

[PDF][PDF] Genomic DNA isolation from human whole blood samples by non enzymatic salting out method

S Suguna, DH Nandal, S Kamble, A Bharatha… - Int J pharm pharm …, 2014 - researchgate.net
Introduction: Human DNA can be extracted from all the nucleated cells such as hair, tissue,
blood etc. certain sources contain high levels of proteins & many types of secondary …

A comparative evaluation of four DNA extraction protocols from whole blood sample

M Ghaheri, D Kahrizi, K Yari, A Babaie… - Cellular and Molecular …, 2016 - cellmolbiol.org
All organisms have Deoxyribonucleic acid (DNA) within their cells. DNA is a complex
molecule that contains all of the information necessary to build and maintain an organism …

Association of IL-10 (− 1082 A/G) and IL-6 (− 174 G/C) gene polymorphism with type 2 diabetes mellitus in Ethiopia population

B Ayelign, M Negash, H Andualem… - BMC endocrine …, 2021 - Springer
Abstract Background Interleukin (IL)-6 and IL-10 are the most important cytokine with pro
and anti-inflammatory activities, respectively. Dysregulation of IL-6 and IL-10 are associated …

[HTML][HTML] Microsatellite (SSR) amplification by PCR usually led to polymorphic bands: Evidence which shows replication slippage occurs in extend or nascent DNA …

A Hosseinzadeh-Colagar… - Molecular biology …, 2016 - ncbi.nlm.nih.gov
Microsatellites or simple sequence repeats (SSRs) are very effective molecular markers in
population genetics, genome mapping, taxonomic study and other large-scale studies …

Persistent basal ganglia involvement in aminoacylase-1 deficiency: expanding imaging findings and review of literature

MF Mohammadi, A Dehghani, K Zarabadi… - Irish Journal of Medical …, 2024 - Springer
Abstract Background Aminoacylase-1 deficiency (ACY1D) is an autosomal recessive rare
inborn error of metabolism, which is caused by disease-causing variants in the ACY1. This …

Evaluation of a modified salt-out method for DNA extraction from whole blood lymphocytes: A simple and economical method for gene polymorphism

A Mohammadpour - Pharmaceutical and Biomedical Research, 2018 - pbr.mazums.ac.ir
The isolation of DNA, RNA, and protein is very important in genetic analysis and molecular
diagnosis (1). Moreover, a DNA extraction with high concentration and purity is required to …

Quercetin arrests in G2 phase, upregulates INXS LncRNA and downregulates UCA1 LncRNA in MCF-7 cells

F Rezaie, MJ Mokhtari, M Kalani - International Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
One of the most prevalent malignancies, which have severe effects on women's health, is
breast cancer. Quercetin, a flavonoid found in vegetables, tea, and fruits, is known to have …

Epilepsia partialis continua a clinical feature of a missense variant in the ADCK3 gene and poor response to therapy

MR Ashrafi, R Haghighi, RS Badv, H Ghabeli… - Journal of Molecular …, 2022 - Springer
Introduction Coenzyme Q10 deficiency can be due to mutations in Coenzyme Q10-
biosynthesis genes (primary) or genes unrelated to biosynthesis (secondary). Primary …