How does chronobiology contribute to the development of diseases in later life

TA Stowe, CA McClung - Clinical Interventions in Aging, 2023 - Taylor & Francis
An increasingly older population is one of the major social and medical challenges we
currently face. Between 2010 and 2050, it is estimated that the proportion of adults over 65 …

Sleep disturbance in Tourette's disorder: Potential underlying mechanisms

EJ Ricketts, V Swisher, DJ Greene, D Silverman… - Current Sleep Medicine …, 2023 - Springer
Abstract Purpose of Review Sleep disturbance is common in TD. However, our
understanding of the pathophysiological mechanisms involved is preliminary. This review …

Using Polygenic Scores for Circadian Rhythms to Predict Wellbeing, Depressive Symptoms, Chronotype, and Health

A Landvreugd, R Pool, MG Nivard… - Journal of Biological …, 2024 - journals.sagepub.com
The association between circadian rhythms and diseases has been well established, while
the association with mental health is less explored. Given the heritable nature of circadian …

Glycyrrhizic acid treatment ameliorates anxiety-like behaviour via GLT1 and Per1/2-dependent pathways

S Ma, Y Chong, R Zhang, W Quan, J Gui, L Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance As a traditional Chinese medicinal herb, Glycyrrhiza.
Uralensis Fisch.(licorice root, chinese name: Gancao) has a variety of medicinal values and …

Evaluating the Genetic Role of Circadian Clock Genes in Parkinson's Disease

Y Xiang, JJ Huang, Y Wang, XR Huang, Q Zeng… - Molecular …, 2023 - Springer
Increasing evidence suggests that circadian dysfunction is related to Parkinson's disease
(PD). However, the role of circadian clock genes in PD is still poorly understood. This study …

[HTML][HTML] Hypothalamic A11 nuclei regulate the circadian rhythm of spinal mechanonociception through dopamine receptors and clock gene expression

C Piña-Leyva, M Lara-Lozano, M Rodríguez-Sánchez… - Life, 2022 - mdpi.com
Several types of sensory perception have circadian rhythms. The spinal cord can be
considered a center for controlling circadian rhythms by changing clock gene expression …

The Dopaminergic System Modulates the Electrophysiological Activity of the Suprachiasmatic Nucleus Dependent on the Circadian Cycle

S Mesgar, K Eskandari, H Karimian-Sani-Varjovi… - Neurochemical …, 2023 - Springer
The suprachiasmatic nucleus of the hypothalamus (SCN) controls mammalian circadian
rhythms. Circadian rhythms influence the dopaminergic system, and dopaminergic tone …

Advancements in therapeutic strategies: The role of bmal1 in enhancing cerebral glioma angiogenesis in athletes through the modulation of vegf and ang2

L Angsi, L Xiao, K Jianxin, H Ke, H Ke… - Revista multidisciplinar de …, 2023 - rimcafd.com
Objective: This study aims to investigate the role of BMAL1 in promoting angiogenesis in
cerebral glioma among athletes by regulating vascular endothelial growth factor (VEGF) and …