The gut microbiome in adult and pediatric functional gastrointestinal disorders

A Shin, GA Preidis, R Shulman, PC Kashyap - Clinical Gastroenterology …, 2019 - Elsevier
The importance of gut microbiota in gastrointestinal (GI) physiology was well described, but
our ability to study gut microbial ecosystems in their entirety was limited by culture-based …

Autism spectrum disorder as a brain-gut-microbiome axis disorder

V Saurman, KG Margolis, RA Luna - Digestive diseases and sciences, 2020 - Springer
While there are numerous medical comorbidities associated with ASD, gastrointestinal (GI)
issues have a significant impact on quality of life for these individuals. Recent findings …

Mixed viral-bacterial infections and their effects on gut microbiota and clinical illnesses in children

S Mathew, MK Smatti, K Al Ansari, GK Nasrallah… - Scientific reports, 2019 - nature.com
Acute gastroenteritis remains a major cause of morbidity and mortality among young
children worldwide. It accounts for approximately 1.34 million deaths annually in children …

A distinct faecal microbiota and metabolite profile linked to bowel habits in patients with irritable bowel syndrome

B Ahluwalia, C Iribarren, MK Magnusson, J Sundin… - Cells, 2021 - mdpi.com
Patients with irritable bowel syndrome (IBS) are suggested to have an altered intestinal
microenvironment. We therefore aimed to determine the intestinal microenvironment profile …

Functional gastrointestinal disorders and the microbiome—what is the best strategy for moving microbiome-based therapies for functional gastrointestinal disorders …

RAT Mars, M Frith, PC Kashyap - Gastroenterology, 2021 - Elsevier
There have been numerous human studies reporting associations between the intestinal
microbiome and functional gastrointestinal disorders (FGIDs), and independently animal …

Systematic metabolic profiling of mice with dextran sulfate sodium-induced colitis

D Xie, F Li, D Pang, S Zhao, M Zhang… - Journal of …, 2021 - Taylor & Francis
Purpose Inflammatory bowel diseases (IBD) are a chronic inflammatory disease, which
affects almost all tissues in the body. Previous studies mainly focused on breathing, fecal …

[HTML][HTML] Leveraging human microbiome features to diagnose and stratify children with irritable bowel syndrome

EB Hollister, N Oezguen, BP Chumpitazi… - The Journal of Molecular …, 2019 - Elsevier
Accurate diagnosis and stratification of children with irritable bowel syndrome (IBS) remain
challenging. Given the central role of recurrent abdominal pain in IBS, we evaluated the …

Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and …

AH Keshteli, KL Madsen, R Mandal… - Alimentary …, 2019 - Wiley Online Library
Background Evaluation of the metabolomic profile of patients with irritable bowel syndrome
offers an opportunity to identify novel pathophysiological targets and biomarkers that could …

Effects of different feeding methods on the structure, metabolism, and gas production of infant and toddler intestinal flora and their mechanisms

X Pi, H Hua, Q Wu, X Wang, X Wang, J Li - Nutrients, 2022 - mdpi.com
In this study, we evaluated the effects of different feeding methods on the characteristics of
intestinal flora and gas production in infants and toddlers by using an in vitro simulated …

[HTML][HTML] Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel …

WX Zhang, Y Zhang, G Qin, KM Li, W Wei… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Fecal metabolites are associated with gut visceral sensitivity, mucosal
immune function and intestinal barrier function, all of which have critical roles in the …