[HTML][HTML] Microneedles: A smart approach and increasing potential for transdermal drug delivery system

T Waghule, G Singhvi, SK Dubey, MM Pandey… - Biomedicine & …, 2019 - Elsevier
The most widely used methods for transdermal administration of the drugs are hypodermic
needles, topical creams, and transdermal patches. The effect of most of the therapeutic …

Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment

ZJ Krysiak, U Stachewicz - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The skin is a complex layer system and the most important barrier between the environment
and the organism. In this review, we describe some widespread skin problems, with a focus …

Improved topical drug delivery: Role of permeation enhancers and advanced approaches

V Hmingthansanga, N Singh, S Banerjee, S Manickam… - Pharmaceutics, 2022 - mdpi.com
The delivery of drugs via transdermal routes is an attractive approach due to ease of
administration, bypassing of the first-pass metabolism, and the large skin surface area …

[HTML][HTML] Localised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis

IA Tekko, AD Permana, L Vora, T Hatahet… - European Journal of …, 2020 - Elsevier
Methotrexate (MTX), typically used as its sodium salt (MTX Na), is a first-line treatments for
moderate to severe psoriasis, showing good efficacy. However, its systemic administration is …

New insights in topical drug delivery for skin disorders: from a nanotechnological perspective

N Raina, R Rani, VK Thakur, M Gupta - ACS omega, 2023 - ACS Publications
Skin, the largest organ in humans, is an efficient route for the delivery of drugs as it
circumvents several disadvantages of the oral and parenteral routes. These advantages of …

Functional nano-systems for transdermal drug delivery and skin therapy

L Liu, W Zhao, Q Ma, Y Gao, W Wang, X Zhang… - Nanoscale …, 2023 - pubs.rsc.org
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for
therapeutic agent administration. Recently, functional nano-systems have been …

Lipid-based nanosystems as a tool to overcome skin barrier

M Sguizzato, E Esposito, R Cortesi - International journal of molecular …, 2021 - mdpi.com
Skin may be affected by many disorders that can be treated by topical applications of drugs
on the action site. With the advent of nanotechnologies, new efficient delivery systems have …

Nanoparticle-enabled transdermal drug delivery systems for enhanced dose control and tissue targeting

BC Palmer, LA DeLouise - Molecules, 2016 - mdpi.com
Transdermal drug delivery systems have been around for decades, and current
technologies (eg, patches, ointments, and creams) enhance the skin permeation of low …

Metal-organic frameworks as potential drug delivery systems

CY Sun, C Qin, XL Wang, ZM Su - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Metal-organic frameworks (MOFs) are a unique class of hybrid porous solids
based on metals and organic linkers. Compared to traditional porous materials, they …

Advances in xanthan gum-based systems for the delivery of therapeutic agents

M Jadav, D Pooja, DJ Adams, H Kulhari - Pharmaceutics, 2023 - mdpi.com
In the last three decades, polymers have contributed significantly to the improvement of drug
delivery technologies by enabling the controlled and sustained release of therapeutic …