Nanopore DNA sequencing technologies and their applications towards single-molecule proteomics

A Dorey, S Howorka - Nature chemistry, 2024 - nature.com
Sequencing of nucleic acids with nanopores has emerged as a powerful tool offering rapid
readout, high accuracy, low cost and portability. This label-free method for sequencing at the …

Decoding DNA, RNA and peptides with quantum tunnelling

M Di Ventra, M Taniguchi - Nature nanotechnology, 2016 - nature.com
Drugs and treatments could be precisely tailored to an individual patient by extracting their
cellular-and molecular-level information. For this approach to be feasible on a global scale …

Identification of single nucleotides in MoS2 nanopores

J Feng, K Liu, RD Bulushev, S Khlybov… - Nature …, 2015 - nature.com
The size of the sensing region in solid-state nanopores is determined by the size of the pore
and the thickness of the pore membrane, so ultrathin membranes such as graphene and …

Characterization and application of supramolecular junctions

X Li, W Ge, S Guo, J Bai, W Hong - … Chemie International Edition, 2023 - Wiley Online Library
The convergence of supramolecular chemistry and single‐molecule electronics offers a new
perspective on supramolecular electronics, and provides a new avenue toward …

The evolution of nanopore sequencing

Y Wang, Q Yang, Z Wang - Frontiers in genetics, 2015 - frontiersin.org
The “1000Genome”projecthasbeendrawingincreasingattention….Nanoporesequencing,
thethird-generation,isbelievedtobeoneofthemostpromisingsequ…“ 1000 Genome” while the …

Fabricating nanopores with diameters of sub-1 nm to 3 nm using multilevel pulse-voltage injection

I Yanagi, R Akahori, T Hatano, K Takeda - Scientific reports, 2014 - nature.com
To date, solid-state nanopores have been fabricated primarily through a focused-electronic
beam via TEM. For mass production, however, a TEM beam is not suitable and an …

Sub‐5 nm metal nanogaps: physical properties, fabrication methods, and device applications

Y Yang, C Gu, J Li - Small, 2019 - Wiley Online Library
Sub‐5 nm metal nanogaps have attracted widespread attention in physics, chemistry,
material sciences, and biology due to their physical properties, including great plasmon …

Detection of post-translational modifications in single peptides using electron tunnelling currents

T Ohshiro, M Tsutsui, K Yokota, M Furuhashi… - Nature …, 2014 - nature.com
Post-translational modifications alter the properties of proteins through the cleavage of
peptide bonds or the addition of a modifying group to one or more amino acids,,,,,,. These …

Solid-state nanopores towards single-molecule DNA sequencing

Y Goto, R Akahori, I Yanagi, K Takeda - Journal of human genetics, 2020 - nature.com
Nanopore DNA sequencing offers a new paradigm owing to its extensive potential for long-
read, high-throughput detection of nucleotide modification and direct RNA sequencing …

Existing and emerging technologies for tumor genomic profiling

LE MacConaill - Journal of Clinical Oncology, 2013 - ascopubs.org
Ongoing global genome characterization efforts are revolutionizing our knowledge of cancer
genomics and tumor biology. In parallel, information gleaned from these studies on driver …