MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

MicroRNA regulation of RNA virus replication and pathogenesis

DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

L Vojtech, S Woo, S Hughes, C Levy… - Nucleic acids …, 2014 - academic.oup.com
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but
which could also interfere with defense against infection. Each ejaculate contains trillions of …

Immunopathology of RSV: an updated review

HC Bergeron, RA Tripp - Viruses, 2021 - mdpi.com
RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …

MicroRNA mimics or inhibitors as antiviral therapeutic approaches against COVID-19

C Hum, J Loiselle, N Ahmed, TA Shaw, C Toudic… - Drugs, 2021 - Springer
Coronaviruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …

The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

R Mirzaei, F Mahdavi, F Badrzadeh… - International …, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID-19) pandemic has imposed significant public
health problems for the human populations worldwide after the 1918 influenza A virus …

[HTML][HTML] High affinity of host human microRNAs to SARS-CoV-2 genome: An in silico analysis

S Jafarinejad-Farsangi, MM Jazi… - Non-coding RNA …, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) caused by a novel
betacoronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Respiratory syncytial virus infection changes cargo composition of exosome released from airway epithelial cells

HS Chahar, T Corsello, AS Kudlicki, N Komaravelli… - Scientific reports, 2018 - nature.com
Exosomes are microvesicles known to carry biologically active molecules, including RNA,
DNA and proteins. Viral infections can induce profound changes in exosome composition …

Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

K Sedeyn, B Schepens, X Saelens - PLoS pathogens, 2019 - journals.plos.org
Human respiratory syncytial virus (RSV) is the most important cause of acute lower
respiratory tract disease in infants worldwide. As a first line of defense against respiratory …

microRNAs in viral acute respiratory infections: immune regulation, biomarkers, therapy, and vaccines

SA Leon-Icaza, M Zeng, AG Rosas-Taraco - ExRNA, 2019 - Springer
MicroRNAs (miRNAs) are single-stranded RNAs of 17–24 nt. These molecules regulate
gene expression at the post-transcriptional level and are differentially expressed in viral …