Recent advances in β-glucosidase sequence and structure engineering: a brief review

B Ouyang, G Wang, N Zhang, J Zuo, Y Huang, X Zhao - Molecules, 2023 - mdpi.com
β-glucosidases (BGLs) play a crucial role in the degradation of lignocellulosic biomass as
well as in industrial applications such as pharmaceuticals, foods, and flavors. However, the …

Stabilization challenges and aggregation in protein-based therapeutics in the pharmaceutical industry

M Rahban, F Ahmad, MA Piatyszek, T Haertlé, L Saso… - RSC …, 2023 - pubs.rsc.org
Protein-based therapeutics have revolutionized the pharmaceutical industry and become
vital components in the development of future therapeutics. They offer several advantages …

Therapeutic protein-based vaccines

S Ahmad, V Dahiya, A Vibhuti, RP Pandey… - Protein-based …, 2023 - Springer
Infectious diseases are reported worldwide, and the emergence of highly mutated antibiotic-
resistant strains is a major concern globally. Developing efficient vaccines is the only way to …

Structural analysis of biomacromolecules using circular dichroism spectroscopy

X Zhao, Y Wang, D Zhao - … Methods to Study Biomolecular Structure and …, 2023 - Elsevier
The chirality of biomacromolecules renders circular dichroism (CD) detection a method to
measure their multiscale structures. This chapter reviews the applications of CD …

Complementary spectroscopy studies and potential activities of levan-type fructan produced by Bacillus paralicheniformis ND2

Y El Halmouch, HAH Ibrahim, NM Dofdaa… - Carbohydrate …, 2023 - Elsevier
This study aimed at the production of marine bacterial exopolysaccharides (EPS) as
biodegradable and nontoxic biopolymers, competing the synthetic derivatives, with detailed …

Fungal vaccine development: State of the art and perspectives using Immunoinformatics

MM Inácio, ALE Moreira, VRM Cruz-Leite, K Mattos… - Journal of Fungi, 2023 - mdpi.com
Fungal infections represent a serious global health problem, causing damage to health and
the economy on the scale of millions. Although vaccines are the most effective therapeutic …

In‐depth analysis of the Sirtuin 5‐regulated mouse brain malonylome and succinylome using library‐free data‐independent acquisitions

J Bons, J Rose, R Zhang, JB Burton, C Carrico… - …, 2023 - Wiley Online Library
Post‐translational modifications (PTMs) dynamically regulate proteins and biological
pathways, typically through the combined effects of multiple PTMs. Lysine residues are …

Fluorescence-based protein stability monitoring—a review

N Gooran, K Kopra - International Journal of Molecular Sciences, 2024 - mdpi.com
Proteins are large biomolecules with a specific structure that is composed of one or more
long amino acid chains. Correct protein structures are directly linked to their correct function …

Rosmarinic Acid-Rich Perilla frutescens Extract-Derived Silver Nanoparticles: A Green Synthesis Approach for Multifunctional Biomedical Applications including …

VR Netala, T Hou, SS Sana, H Li, Z Zhang - Molecules, 2024 - mdpi.com
This study describes a simple, cost-effective, and eco-friendly method for synthesizing silver
nanoparticles using a rosmarinic acid extract from Perilla frutescens (PFRAE) as the …

Nanobody-peptide-conjugate (NPC) for passive immunotherapy against SARS-CoV-2 variants of concern (VoC): a prospective pan-coronavirus therapeutics

M Panda, E Kalita, S Singh, K Kumar, VK Prajapati - Molecular Diversity, 2023 - Springer
The COVID-19 crisis, incited by the zoonotic SARS-CoV-2 virus, has quickly escalated into a
catastrophic public health issue and a grave threat to humankind owing to the advent of …