Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Background Serum albumin is the most abundant protein in the blood and cerebrospinal
fluid and plays a fundamental role in the distribution of essential transition metal ions in the …

Patients having experienced the ischemia-reperfusion process are particularly vulnerable to
subsequent heart attacks because this process can induce myocardial fibrosis, hallmarked …

The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Peptides and proteins with N‐terminal amino acid sequences NH2‐Xxx‐His (XH) and NH2‐
Xxx‐Zzz‐His (XZH) form well‐established high‐affinity CuII‐complexes. Key examples are …

Allosteric regulation is gaining increasing attention as a basis for the production of stimuli-
responsive materials in many research areas including DNA nanotechnology. We expected …

Accumulation of amyloid beta (Aβ) peptide and its aggregates in the human brain is
considered as one of the hallmarks of Alzheimer's disease (AD). The polymorphic oligomers …

Copper (II) binding to the amyloid-β peptide has been proposed to be a key event in the
cascade leading to Alzheimer's disease. As a direct consequence, the strength of the Cu (II) …

Host‐defense peptides (HDPs) feature evolution‐tested potency against life‐threatening
pathogens. While piscidin 1 (p1) and piscidin 3 (p3) are homologous and potent fish HDPs …

Copper ions have been proposed to play a central role in the amyloid cascade process
linked to the development of Alzheimer disease (AD). Involvement in both the amyloid-β (Aβ) …