The cytotoxicity of microcystin-LR: ultrastructural and functional damage of cells

K Ge, X Du, H Liu, R Meng, C Wu, Z Zhang… - Archives of …, 2024 - Springer
Abstract Microcystin-LR (MC-LR) is a toxin produced by cyanobacteria, which is widely
distributed in eutrophic water bodies and has multi-organ toxicity. Previous cytotoxicity …

Transgenerational effects of extracts containing Microcystin-LR exposure on reproductive toxicity and offspring growth inhibition in a model organism zebrafish

Q Yang, L Huang, N Yang, H Cui, Y Zhao, Z Li, Y Tong - Aquatic Toxicology, 2024 - Elsevier
Cyanobacteria cell lysates release numerous toxic substances (eg, cyanotoxins) into the
water, posing a serious threat to human health and aquatic ecosystems. Microcystins (MCs) …

Microcystin-LR activates serine/threonine kinases and alters the phosphoproteome in human HepaRG cells

VO Ikumawoyi, KD Lynch, DT Iverson, MR Call, GE Yue… - Toxicon, 2024 - Elsevier
Microcystin-LR (MCLR) exposure has been associated with development of hepatocellular
carcinoma (HCC). Many of the carcinogenic mechanisms for MCLR have been attributed to …

Perfluorooctane sulfonate promotes the migration of colorectal cancer cells by inducing epithelial-mesenchymal transition

F Li, L Chen, BX Peng, Y Lei, M Li, LH Guo - Journal of Environmental …, 2024 - Elsevier
The potential association between colorectal cancer (CRC) and environmental pollutants is
worrisome. Previous studies have found that some perfluoroalkyl acids, including …

Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure

H Ma, C Loscher, A Parle-McDermott, J Fitzgerald… - Frontiers in …, 2024 - frontiersin.org
Introduction: Globally, the need for measuring exposure to algal toxins has become urgent
due to ever-increasing reports of contamination in sea and freshwater, in shellfish and fish …