The methyl group is one of the most commonly occurring carbon fragments in small‐
molecule drugs. This simplest alkyl fragment appears in more than 67% of the top‐selling …

Sulfones are flexible functional groups that can act as nucleophiles, electrophiles, or even
radicals. Changing the reaction conditions can completely alter the reactivity of a sulfonyl …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

The development of new asymmetric methodologies that afford different structures in an
enantioselective fashion is one of the most exciting goals for chemists nowadays. In this …

Asymmetric organocatalysis has become a powerful tool for the synthesis of optically active
compounds. Whereas early research mainly focused on combining simple reagents as a …

Recent years have witnessed an explosive growth in the field of amino organocatalysis,
especially in asymmetric enamine and iminium catalysis. Except for the obvious interaction …

Asymmetric catalysis is a rapidly evolving field in synthetic chemistry. This is due to the
growing needs of stereoselective synthetic routes to access enantiopure natural products …

An efficient synthesis of spiropyrazolones based on organocatalysis is described. The
reaction between pyrazolones, enolizable aldehydes and enals is catalyzed by secondary …

Working together: The title reactions were achieved in high yields with high ee values (see
scheme,(DHQD) 2 AQN= hydroquinidine (anthraquinone‐1, 4‐diyl) diether). The …

Chiral sulfones extensively exist in drugs, agricultural chemicals, chiral organic
intermediates, and functional materials. Their importance causes the rapid development of …