Role of Pyroptosis in Endometrial Cancer and Its Therapeutic Regulation

A Al Mamun, P Geng, S Wang… - Journal of Inflammation …, 2024 - Taylor & Francis
Pyroptosis is an inflammatory cell death induced by inflammasomes that release several pro-
inflammatory mediators such as interleukin-18 (IL-18) and interleukin-1β (IL-1β). Pyroptosis …

Macrophage Perspectives in Liver Diseases: Programmed Death, Related Biomarkers, and Targeted Therapy

Z Qian, W Xiong, X Mao, J Li - Biomolecules, 2024 - mdpi.com
Macrophages, as important immune cells of the organism, are involved in maintaining
intrahepatic microenvironmental homeostasis and can undergo rapid phenotypic changes in …

A pyroptosis-related gene signature for prognosis prediction in hepatocellular carcinoma

Y Chen, Y Zhu, Y Dong, H Li, C Gao, G Zhu, X Mi… - Frontiers in …, 2023 - frontiersin.org
Introduction Hepatocellular carcinoma (HCC) is one of the most invasive cancers with a low
5-year survival rate. Pyroptosis, a specialized form of cell death, has shown its association …

T lymphocyte-mediated pyroptosis: A new regulatory mechanism in non-viral liver disease

W Xiong, Z Qian, X Mao, J Li - Clinics and Research in Hepatology and …, 2023 - Elsevier
T lymphocyte-mediated pyroptosis plays an important role in the development of non-viral
liver diseases. Pyroptosis as a programmed cell death process, has been a hot topic of …

Identification of pyroptosis subtypes and prognosis model of hepatocellular carcinoma based on pyroptosis‐related genes

H Xie, G Huang, H Mai, J Chen, R Na… - Cancer …, 2024 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is a common malignant tumor with poor
prognosis. Pyroptosis, a type of programmed cell death, regulates tumor cell development …

Machine learning screening for molecular subtyping of Alzheimer's disease based on pyroptosis-related genes

B Hu, Y Bai, W Gao - 2024 - researchsquare.com
The aim of the present research was to find the Alzheimer's disease (AD) disease
characteristic genes (DCGs) by machine learning algorithms, and constructed and verified …

The effect of CMTM6 on the anti-HCC efficacy of iNKT cells via stabilizing PD-L1 in an experimental investigation

J Teng, Y Wang, M Zhang, Z Li, Q Liu, W Lv, M Meng - 2023 - researchsquare.com
Background CMTM6 is a key regulator of PD-L1. The purpose of this study is to see whether
CMTM6 impacts iNKT cells infiltration into hepatocellular carcinoma (HCC) and whether …