Technological development and advances in single-photon emission computed tomography/computed tomography

Y Seo, C Mari, BH Hasegawa - Seminars in nuclear medicine, 2008 - Elsevier
Single-photon emission computed tomography/computed tomography (SPECT/CT) has
emerged during the past decade as a means of correlating anatomical information from CT …

SPECT/CT in tumor imaging: technical aspects and clinical applications

Z Keidar, O Israel, Y Krausz - Seminars in nuclear medicine, 2003 - Elsevier
Diagnostic imaging has gained a major role in the management of patients with cancer and
has made a further step forward with the introduction of fusion techniques into the field. This …

EANM Dosimetry Committee guidelines for bone marrow and whole-body dosimetry

C Hindorf, G Glatting, C Chiesa, O Lindén… - European journal of …, 2010 - Springer
Introduction The level of administered activity in radionuclide therapy is often limited by
haematological toxicity resulting from the absorbed dose delivered to the bone marrow. The …

Accurate dosimetry in 131I radionuclide therapy using patient-specific, 3-dimensional methods for SPECT reconstruction and absorbed dose calculation

YK Dewaraja, SJ Wilderman, M Ljungberg… - Journal of Nuclear …, 2005 - Soc Nuclear Med
131I radionuclide therapy studies have not shown a strong relationship between tumor
absorbed dose and response, possibly due to inaccuracies in activity quantification and …

The impact of PET and SPECT on dosimetry for targeted radionuclide therapy

G Flux, M Bardies, M Monsieurs, S Savolainen… - … für medizinische Physik, 2006 - Elsevier
Targeted radionuclide therapy (TRT) is an increasingly used treatment modality for a range
of cancers. To date, few treatments have involved the use of dosimetry either to plan …

The fusion of anatomic and physiologic imaging in the management of patients with cancer

O Israel, Z Keidar, G Iosilevsky, L Bettman… - Seminars in nuclear …, 2001 - Elsevier
Imaging is of major clinical importance in the noninvasive evaluation and management of
patients with cancer. Computed tomography (CT) and other anatomic imaging modalities …

Gallium-67 scintigraphy: a cornerstone in functional imaging of lymphoma

E Even-Sapir, O Israel - European journal of nuclear medicine and …, 2003 - Springer
Abstract Until recently, gallium-67 scintigraphy (GS) has been the best available functional
imaging modality for evaluating patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's …

An activity quantification method based on registration of CT and whole-body scintillation camera images, with application to 131I

K Sjögreen, M Ljungberg, SE Strand - Journal of Nuclear …, 2002 - Soc Nuclear Med
This article presents a new method for conjugate view activity quantification for 131I-labeled
monoclonal antibody distribution. Methods: The method is based on the combined use of …

3-D Monte Carlo-based scatter compensation in quantitative I-131 SPECT reconstruction

YK Dewaraja, M Ljungberg… - IEEE transactions on …, 2006 - ieeexplore.ieee.org
We have implemented highly accurate Monte Carlo based scatter modeling (MCS) with 3-D
ordered subsets expectation maximization (OSEM) reconstruction for I-131 single photon …

Update on hybrid conjugate-view SPECT tumor dosimetry and response in 131I-tositumomab therapy of previously untreated lymphoma patients

KF Koral, Y Dewaraja, J Li, Q Lin… - Journal of Nuclear …, 2003 - Soc Nuclear Med
A study of the use of 131I-labeled tositumomab, preceded by an unlabeled tositumomab
predose, for therapy of 76 previously untreated non-Hodgkin's lymphoma patients has been …