Multiple Sclerosis: Glial Cell Diversity in Time and Space

SM Kooistra, L Schirmer - Glia, 2024 - Wiley Online Library
Multiple sclerosis (MS) is the most prevalent human inflammatory disease of the central
nervous system with demyelination and glial scar formation as pathological hallmarks. Glial …

Spatial Transcriptomic Analysis Identifies a SERPINA3-Expressing Astrocytic State Associated with the Human Neuritic Plaque Microenvironment

B Karaahmet, Y Zhang, L Duquesne, A Sigalov… - bioRxiv, 2024 - biorxiv.org
Single-nucleus transcriptomic studies have revealed glial cell states associated with
Alzheimer's disease; however, these nuclei are dissociated from the complex architecture of …