The estrogen-related receptors (ERRs) comprise a small group of orphan nuclear receptor
transcription factors. The ERRα and ERRγ isoforms play a central role in the regulation of …

Background Modern lifestyles, especially high-caloric intake and physical inactivity,
contribute to the increased prevalence of non-alcoholic fatty liver disease (NAFLD), which …

Background & Aims Non-alcoholic fatty liver disease (NAFLD) is strongly associated with
obesity and type 2 diabetes. Thioredoxin-interacting protein (TXNIP) regulates the cellular …

Excessive gluconeogenesis can lead to hyperglycemia and diabetes through as yet
incompletely understood mechanisms. Herein, we show that hepatic ZBTB22 expression is …

Mouse olfactory receptor 544 (Olfr544) is ectopically expressed in varied extra-nasal organs
with tissue specific functions. Here, we investigated the functionality of Olfr544 in skeletal …

Extremely low gestational age neonates (ELGANs) are born in a relatively hyperoxic
environment with weak antioxidant defenses, placing them at high risk for mitochondrial …

Krüppel-like factor 14 (KLF14) is a member of the Cys 2/His 2 zinc-finger DNA-binding
proteins. Despite strong evidence showing that a polymorphism in the Klf14 gene is closely …

This study was designed to evaluate the effects of Platycodon grandiflorum A. DC. ethanolic
extract (PG) on obesity in brown/white preadipocytes. The effect of PG on the differentiation …

A bstract Background and aims Free fatty acids (FFAs) are one of the important regulators of
the progression of nonalcoholic fatty liver disease. The FFAs are shown to modulate the …

The mouse olfactory receptor Olfr544 is expressed in several non-olfactory tissues and has
been suggested as a functional receptor regulating different signaling pathways. However …