Genetically encoded biosensors are crucial for enhancing our understanding of how
molecules regulate biological systems. Small molecule biosensors, in particular, help us …

Abstract Adeno‐associated virus (AAV)‐based therapies are recognized as one of the most
potent next‐generation treatments for inherited and genetic diseases. However, several …

Motivation: BioJava is an open-source project for processing of biological data in the Java
programming language. We have recently released a new version (3.0. 5), which is a major …

AP205 is a single-stranded RNA bacteriophage that has a coat protein sequence not similar
to any other known single-stranded RNA phage. Here, we report an atomic-resolution model …

All land plants encode large multigene families of xyloglucan endotransglucosylase/
hydrolases (XTHs), plant-specific enzymes that cleave and reconnect plant cell-wall …

Rhodopsins are photochemically reactive membrane proteins that covalently bind retinal
chromophores. Type I rhodopsins are found in both prokaryotes and eukaryotic microbes …

Over 30 years ago, an intriguing posttranslational modification was found responsible for
creating concanavalin A (conA), a carbohydrate-binding protein from jack bean (Canavalia …

Highlights•Domain swapping refers to the exchange of structural elements between protein
domains.•Experiments show that tandem homologous domains are prone to domain …

The recent breakthrough from AlphaFold2 and RoseTTAFold set a profound milestone for
solving the protein folding problem, but they were not explicitly trained to predict protein …

Research in the last two decades has increasingly demonstrated that RNA has capabilities
comparable to those of proteins, for example the ability to form intricate 3D structures …