[HTML][HTML] Oxidative stress and the amyloid beta peptide in Alzheimer's disease

C Cheignon, M Tomas, D Bonnefont-Rousselot… - Redox biology, 2018 - Elsevier
Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

Oxidant/antioxidant imbalance in Alzheimer's disease: therapeutic and diagnostic prospects

J Wojsiat, KM Zoltowska… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

The cellular and molecular processes associated with scopolamine-induced memory deficit: A model of Alzheimer's biomarkers

K San Tang - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) is neurodegenerative disorder that is associated with memory and
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …

Copper toxicity links to pathogenesis of Alzheimer's disease and therapeutics approaches

HW Ejaz, W Wang, M Lang - International Journal of Molecular Sciences, 2020 - mdpi.com
Alzheimer's disease (AD) is an irreversible, age-related progressive neurological disorder,
and the most common type of dementia in aged people. Neuropathological lesions of AD …

Oxidative stress and antioxidant defenses in mild cognitive impairment: A systematic review and meta-analysis

G Nantachai, A Vasupanrajit, C Tunvirachaisakul… - Ageing Research …, 2022 - Elsevier
This study aims to systematically review and meta-analyze the nitro-oxidative stress
(O&NS)/antioxidant (ANTIOX) ratio in the peripheral blood of people with mild cognitive …

[HTML][HTML] Sterubin protects against chemically-induced Alzheimer's disease by reducing biomarkers of inflammation-IL-6/IL-β/TNF-α and oxidative stress-SOD/MDA in …

I Kazmi, FA Al-Abbasi, M Afzal, MS Nadeem… - Saudi Journal of …, 2023 - Elsevier
Sterubin, a flavanone is an active chemical compound that possesses neuroprotective
activity. The current investigation was intended to assess the sterubin effect in scopolamine …

Competitive electrochemical immunosensor for the detection of unfolded p53 protein in blood as biomarker for Alzheimer's disease

O Amor-Gutiérrez, E Costa-Rama, N Arce-Varas… - Analytica chimica …, 2020 - Elsevier
Alzheimer's disease is one of the most common causes of dementia nowadays, and its
prevalence increases over time. Because of this and the difficulty of its diagnosis, accurate …

Early detection and prevention of Alzheimer's disease: role of oxidative markers and natural antioxidants

J Arslan, H Jamshed, H Qureshi - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
Oxidative stress (OS) contributes to Alzheimer's disease (AD) pathology. OS can be a result
of increased reactive oxygen/nitrogen species, reduced antioxidants, oxidatively damaged …

The pleiotropic role of p53 in functional/dysfunctional neurons: Focus on pathogenesis and diagnosis of Alzheimer's disease

G Abate, GB Frisoni, JC Bourdon, S Piccirella… - Alzheimer's Research & …, 2020 - Springer
Background Understanding the earliest pathophysiological changes of Alzheimer's disease
(AD) may aid in the search for timely diagnostic biomarkers and effective disease-modifying …

Bifunctional Au@ Pt/Au core@ shell nanoparticles as novel electrocatalytic tags in immunosensing: application for Alzheimer's disease biomarker detection

A Iglesias-Mayor, O Amor-Gutierrez, A Novelli… - Analytical …, 2020 - ACS Publications
In this work, bifunctional core@ shell Au@ Pt/Au NPs are presented as novel tags for
electrochemical immunosensing. Au@ Pt/Au NPs were synthesized following a chemical …