[HTML][HTML] Challenges and opportunities for large-scale electrophysiology with Neuropixels probes

NA Steinmetz, C Koch, KD Harris… - Current opinion in …, 2018 - Elsevier
Electrophysiological methods are the gold standard in neuroscience because they reveal
the activity of individual neurons at high temporal resolution and in arbitrary brain locations …

Revealing neuronal function through microelectrode array recordings

MEJ Obien, K Deligkaris, T Bullmann… - Frontiers in …, 2015 - frontiersin.org
Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …

A fully automated approach to spike sorting

JE Chung, JF Magland, AH Barnett, VM Tolosa… - Neuron, 2017 - cell.com
Understanding the detailed dynamics of neuronal networks will require the simultaneous
measurement of spike trains from hundreds of neurons (or more). Currently, approaches to …

Kilosort: realtime spike-sorting for extracellular electrophysiology with hundreds of channels

M Pachitariu, N Steinmetz, S Kadir, M Carandini… - BioRxiv, 2016 - biorxiv.org
Advances in silicon probe technology mean that in vivo electrophysiological recordings from
hundreds of channels will soon become commonplace. To interpret these recordings we …

Fast and accurate spike sorting of high-channel count probes with KiloSort

M Pachitariu, NA Steinmetz, SN Kadir… - Advances in neural …, 2016 - proceedings.neurips.cc
New silicon technology is enabling large-scale electrophysiological recordings in vivo from
hundreds to thousands of channels. Interpreting these recordings requires scalable and …

Spike sorting for large, dense electrode arrays

C Rossant, SN Kadir, DFM Goodman, J Schulman… - Nature …, 2016 - nature.com
Developments in microfabrication technology have enabled the production of neural
electrode arrays with hundreds of closely spaced recording sites, and electrodes with …

A spike sorting toolbox for up to thousands of electrodes validated with ground truth recordings in vitro and in vivo

P Yger, GLB Spampinato, E Esposito, B Lefebvre… - Elife, 2018 - elifesciences.org
In recent years, multielectrode arrays and large silicon probes have been developed to
record simultaneously between hundreds and thousands of electrodes packed with a high …

[HTML][HTML] Past, present and future of spike sorting techniques

HG Rey, C Pedreira, RQ Quiroga - Brain research bulletin, 2015 - Elsevier
Spike sorting is a crucial step to extract information from extracellular recordings. With new
recording opportunities provided by the development of new electrodes that allow …

Layer-specific modulation of neocortical dendritic inhibition during active wakefulness

W Muñoz, R Tremblay, D Levenstein, B Rudy - Science, 2017 - science.org
γ-Aminobutyric acid (GABA) ergic inputs are strategically positioned to gate synaptic
integration along the dendritic arbor of pyramidal cells. However, their spatiotemporal …

Modelling and analysis of local field potentials for studying the function of cortical circuits

GT Einevoll, C Kayser, NK Logothetis… - Nature Reviews …, 2013 - nature.com
The past decade has witnessed a renewed interest in cortical local field potentials (LFPs)—
that is, extracellularly recorded potentials with frequencies of up to∼ 500 Hz. This is due to …